中国53288名中老年人2型糖尿病和糖尿病前期的患病率及危险因素：一项横断面研究
Prevalence and Risk Factors of Type 2 Diabetes and Prediabetes Among 53,288 Middle-Aged and Elderly Adults in China: A Cross-Sectional Study.
作者信息
Xia Mengdi, Liu Kaixiang, Feng Jie, Zheng Zaiqiong, Xie Xisheng
机构信息
Department of Nephrology, The Second Clinical Medical Institution of North Sichuan Medical College (Nanchong Central Hospital) and Nanchong Key Laboratory of Basic Science & Clinical Research on Chronic Kidney Disease, Nanchong, Sichuan, People's Republic of China.
Department of Nephrology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, People's Republic of China.
出版信息
Diabetes Metab Syndr Obes. 2021 May 3;14:1975-1985. doi: 10.2147/DMSO.S305919. eCollection 2021.
BACKGROUND
Diabetes is a metabolic disorder that causes a heavy burden on healthcare systems worldwide. The aim of this study was to determine the prevalence of type 2 diabetes and prediabetes and its associated factors among eight communities in Nanchong, China.
METHODS
This was an observational cross-sectional study conducted throughout eight communities in Nanchong, China. The participants were 53,288 individuals aged 45 years or older. The participants' characteristics, comorbidities, health behaviors, family history, and dietary intake were assessed. Multinomial logistic regression models were fitted to identify factors associated with type 2 diabetes and prediabetes.
RESULTS
The prevalence of diabetes and prediabetes was 13.9% (95% confidence interval [CI], 13.6-14.2) and 3.1% (95% CI, 2.9-3.2) of the population, respectively. After adjusting for other risk factors, advanced age, overweight, obesity, abdominal obesity, comorbidities, smoking, a family history of diabetes, and Chinese cooking vegetable intake were associated with an increased risk of type 2 diabetes and prediabetes.
CONCLUSION
The prevalence of type 2 diabetes in the Chinese population is rising compared with data from the past. The risk factors of type 2 diabetes and prediabetes identified in this study will aid the identification of individuals at a high-risk of diabetes and the implementation of effective health promotion programs and campaigns.
CLINICAL TRIAL REGISTRY NUMBER
ChiCTR-HOC-17013200.
背景
糖尿病是一种代谢紊乱疾病，给全球医疗系统带来沉重负担。本研究旨在确定中国南充八个社区中2型糖尿病和糖尿病前期的患病率及其相关因素。
方法
这是一项在中国南充八个社区开展的观察性横断面研究。参与者为53288名45岁及以上的个体。评估了参与者的特征、合并症、健康行为、家族史和饮食摄入情况。采用多项逻辑回归模型来确定与2型糖尿病和糖尿病前期相关的因素。
结果
糖尿病和糖尿病前期的患病率分别为人群的13.9%（95%置信区间[CI]，13.6 - 14.2）和3.1%（95%CI，2.9 - 3.2）。在调整其他风险因素后，高龄、超重、肥胖、腹型肥胖、合并症、吸烟、糖尿病家族史以及中式烹饪蔬菜摄入量与2型糖尿病和糖尿病前期风险增加相关。
结论
与过去的数据相比，中国人群中2型糖尿病的患病率正在上升。本研究确定的2型糖尿病和糖尿病前期的风险因素将有助于识别糖尿病高危个体，并实施有效的健康促进计划和活动。
临床试验注册号
ChiCTR-HOC-17013200。
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