Gaillard Dany, Stratford Jennifer M
Department of Cell and Developmental Biology and the Rocky Mountain Taste and Smell Center, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Curr Protoc Mouse Biol. 2016 Dec 1;6(4):380-407. doi: 10.1002/cpmo.18.
The natural like and dislike of foods based on taste is one of the most easily observed behaviors in animals. Animals eat palatable foods and reject aversive foods, which makes measurement of taste perception possible using various behavioral techniques. Three different methods to accurately measure taste behavior are described here. First, two-bottle preference tests evaluate whether a taste compound (tastant) is preferred over water. Second, lickometer tests quantify the like and dislike for multiple concentrations of the same tastant or multiple tastants at the same time. Finally, conditioned taste aversion tests accurately determine the perceived taste threshold for palatable tastants. Together, these diverse methods enable researchers to observe and measure behavioral taste responses in mice to any tastant. © 2016 by John Wiley & Sons, Inc.
基于味道的对食物的自然喜好和厌恶是动物中最容易观察到的行为之一。动物会食用美味的食物并拒绝难吃的食物，这使得使用各种行为技术来测量味觉感知成为可能。这里描述了三种准确测量味觉行为的不同方法。首先，双瓶偏好测试评估一种味觉化合物（味觉剂）是否比水更受青睐。其次，舔舐计数测试量化对同一味觉剂的多种浓度或同时对多种味觉剂的喜欢和厌恶程度。最后，条件性味觉厌恶测试准确确定美味味觉剂的感知味觉阈值。总之，这些不同的方法使研究人员能够观察和测量小鼠对任何味觉剂的行为味觉反应。© 2016约翰威立国际出版公司
