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心房颤动的外科消融:肺静脉电隔离是必需的吗?

Surgical Ablation of Atrial Fibrillation: is Electrical Isolation of the Pulmonary Veins a Must?

作者信息

Maesen Bart, Van-Loo Ines, Pison Laurent, La-Meir Mark

机构信息

Department of Cardio-Thoracic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.

Department of Cardiac Surgery, Universitair Ziekenhuis Brussel, Brussels, Belgium.

出版信息

J Atr Fibrillation. 2016 Jun 30;9(1):1426. doi: 10.4022/jafib.1426. eCollection 2016 Jun-Jul.

Abstract

Ablation of atrial fibrillation (AF) is a well-established treatment option for patients with symptomatic AF refractory to antiarrhythmic drugs. The cornerstone of catheter ablation is electrical isolation of the pulmonary veins, since the pulmonary veins are the most common location for triggers of AF. Electrical reconnection of the pulmonary veins is associated with arrhythmia recurrence and therefore diminishes long-term success of catheter ablation of AF. Therefore, durable pulmonary vein isolation remains a condition sine qua non for catheter ablation of AF. The Cox-Maze procedure is considered an effective surgical cure of AF, however it has never been widely adopted due to its procedural complexity. Since the development of minimal invasive techniques for surgical AF treatment, surgical ablation of AF has regained interest. Most of the minimal invasive surgical AF ablations performed around the globe include pulmonary vein isolation as a part of the procedure. In this review, we explore the necessity of electrical isolation of the pulmonary veins in surgical AF ablation.

摘要

心房颤动(AF)消融术是治疗对抗心律失常药物难治的有症状AF患者的一种成熟治疗选择。导管消融的基石是肺静脉电隔离,因为肺静脉是AF触发因素最常见的部位。肺静脉电重新连接与心律失常复发相关,因此会降低AF导管消融的长期成功率。因此,持久的肺静脉隔离仍然是AF导管消融必不可少的条件。Cox迷宫手术被认为是治疗AF的一种有效手术方法,然而由于其手术复杂性,从未被广泛采用。自从开发出用于手术治疗AF的微创技术以来,AF的外科消融术重新引起了人们的兴趣。全球范围内进行的大多数微创外科AF消融术都包括肺静脉隔离作为手术的一部分。在本综述中,我们探讨了外科AF消融术中肺静脉电隔离的必要性。

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本文引用的文献

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Catheter Ablation for Persistent Atrial Fibrillation.持续性心房颤动的导管消融术
N Engl J Med. 2015 Aug 27;373(9):877-8. doi: 10.1056/NEJMc1508689.
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Electrophysiologic Results After Thoracoscopic Ablation for Chronic Atrial Fibrillation.胸腔镜下慢性心房颤动消融术后的电生理结果
Ann Thorac Surg. 2015 Nov;100(5):1595-602; discussion 1602-3. doi: 10.1016/j.athoracsur.2015.04.127. Epub 2015 Jul 26.

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