Shen Minjie, Niu Junjie, Zhou Haifei, Meng Qian, Gan Minfeng, Yang Huilin
First Affiliated Hospital of Soochow University, Suzhou, China.
Int J Spine Surg. 2016 Oct 5;10:34. doi: 10.14444/3034. eCollection 2016.
The purpose of this study is to evaluate the effect of intradiscal cement leakage on the height of adjacent cement-containing discs and the resulting clinical efficacy after kyphoplasty.
A total of 124 patients were included and classified into two groups: group A included 20 patients with intradiscal leakage, and group B contained 104 patients without intradiscal leakage. The mean follow-up time was 20.56±3.51 months. The height of the corresponding discs in both groups was measured using Farfan's method. Clinical efficacy was assessed using the Visual Analog Scale and Oswestry Disability Index scores at each follow-up time.
The anterior disc height, posterior disc height and Farfan Index significantly decreased in both groups at last follow-up. The disc height reduction was 9.19±2.89% in group A and 3.88±2.70% in group B, which was significantly different between the groups (P<0.01). The disc height reduction rate was 29.39±7.90% in group A and 12.75±8.18% in group B, which was also a statistically significant difference (P<0.01). The VAS and ODI scores improved significantly after surgery and maintained at last follow-up, and there was no statistically significant difference between Groups A and B.
Intradiscal cement leakage was associated with the degeneration of cement-containing disc but did not reduce the clinical efficacy at early stages.
本研究旨在评估经皮椎体后凸成形术中椎间盘内骨水泥渗漏对相邻含骨水泥椎间盘高度的影响以及由此产生的临床疗效。
共纳入124例患者，分为两组：A组20例发生椎间盘内渗漏，B组104例未发生椎间盘内渗漏。平均随访时间为20.56±3.51个月。两组相应椎间盘的高度采用法凡（Farfan）法测量。每次随访时使用视觉模拟评分法和奥斯维斯特里功能障碍指数评分评估临床疗效。
末次随访时两组的椎间盘前缘高度、后缘高度和法凡指数均显著降低。A组椎间盘高度降低9.19±2.89%，B组为3.88±2.70%，两组间差异有统计学意义（P<0.01）。A组椎间盘高度降低率为29.39±7.90%，B组为12.75±8.18%，差异也有统计学意义（P<0.01）。术后视觉模拟评分法和奥斯维斯特里功能障碍指数评分显著改善，并在末次随访时维持，A、B两组间差异无统计学意义。
椎间盘内骨水泥渗漏与含骨水泥椎间盘退变有关，但在早期并不降低临床疗效。
