儿童冷酷无情特质量表（ICU）：信度与遗传度
The Inventory of Callous-Unemotional Traits (ICU) in Children: Reliability and Heritability.
作者信息
Moore Ashlee A, Carney Dever, Moroney Elizabeth, Machlin Laura, Towbin Kenneth E, Brotman Melissa A, Pine Daniel S, Leibenluft Ellen, Roberson-Nay Roxann, Hettema John M
机构信息
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, P.O. Box 980489, Richmond, VA, 23298, USA.
Center for Clinical and Translational Research, Virginia Commonwealth University, Richmond, VA, USA.
出版信息
Behav Genet. 2017 Mar;47(2):141-151. doi: 10.1007/s10519-016-9831-1. Epub 2016 Dec 1.
Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9-14 to examine the reliability and heritability of the parent-report Inventory of Callous-unemotional Traits (ICU) at two assessments approximately 3 weeks apart. Time-specific measurement error was taken into account to obtain a more accurate estimate of the heritability reflecting the latent liability to CU traits. Test-retest reliability was 0.84 and heritability at visit 1 was 39%. The heritability of the latent liability to CU traits was 47%. This latent liability contributed 79% of the variance in ICU score at visit 1 and visit 2. This is the first study to account for measurement error while examining the heritability of CU traits, furthering our understanding of psychopathy in children.
冷酷无情（CU）特质构成了精神病态的核心症状，但尚无研究使用专门设计用于评估CU特质的工具，在社区儿童样本中估计CU特质的遗传力。本研究使用来自339对9至14岁双胞胎的数据，在相隔约3周的两次评估中，检验父母报告的冷酷无情特质量表（ICU）的信度和遗传力。考虑了特定时间的测量误差，以获得更准确的遗传力估计值，反映CU特质的潜在易感性。重测信度为0.84，第一次评估时的遗传力为39%。CU特质潜在易感性的遗传力为47%。这种潜在易感性在第一次和第二次评估时，分别解释了ICU得分变异的79%。这是第一项在检验CU特质遗传力时考虑测量误差的研究，进一步加深了我们对儿童精神病态的理解。
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