冷酷无情特质调节基因和环境对违规与攻击行为的影响：基因×特质交互作用的证据。
Callous-Unemotional Traits Moderate Genetic and Environmental Influences on Rule-Breaking and Aggression: Evidence for Gene × Trait Interaction.
作者信息
Mann Frank D, Tackett Jennifer L, Tucker-Drob Elliot M, Harden K Paige
机构信息
Department of Psychology, University of Texas at Austin.
Department of Psychology, Northwestern University.
出版信息
Clin Psychol Sci. 2018 Jan;6(1):123-133. doi: 10.1177/2167702617730889. Epub 2017 Sep 28.
Previous behavioral genetic research in children has found that conduct problems in the presence of high CU traits are more heritable than conduct problems in the presence of low CU traits -- a gene × trait interaction. The current study replicates and extends this finding using a sample of adolescent twins from the Texas Twin Project, who were assessed for rule-breaking and aggression. We find evidence that genetic influences on CU traits contribute to genetic liability for both rule-breaking and aggressive behavior. CU traits moderate genetic influences on aggressive behavior, such that the heritability of aggression is higher among youth with high levels of CU traits. However, we do not find evidence that CU traits moderate genetic influences on rule-breaking behavior. The continuum of callous-unemotionality and the aggression versus rule-breaking distinction continues to be meaningful and intersecting methods for characterizing heterogeneity in the etiology of antisocial behavior.
先前针对儿童的行为遗传学研究发现，在具有高冷酷无情特质的情况下出现的品行问题比在具有低冷酷无情特质的情况下出现的品行问题更具遗传性——这是一种基因与特质的相互作用。本研究使用来自德克萨斯双胞胎项目的青少年双胞胎样本重复并扩展了这一发现，这些双胞胎接受了违规和攻击行为评估。我们发现有证据表明，对冷酷无情特质的遗传影响会导致违规和攻击行为的遗传易感性。冷酷无情特质会调节对攻击行为的遗传影响，因此在具有高水平冷酷无情特质的青少年中，攻击行为的遗传性更高。然而，我们没有发现证据表明冷酷无情特质会调节对违规行为的遗传影响。冷酷无情的连续体以及攻击与违规的区分仍然是表征反社会行为病因异质性的有意义且相互交叉的方法。
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