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天然聚合物基卡拉胶共混物和复合材料的合成、性能及应用综述

A review on synthesis, properties and applications of natural polymer based carrageenan blends and composites.

作者信息

Zia Khalid Mahmood, Tabasum Shazia, Nasif Muhammad, Sultan Neelam, Aslam Nosheen, Noreen Aqdas, Zuber Mohammad

机构信息

Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.

Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.

出版信息

Int J Biol Macromol. 2017 Mar;96:282-301. doi: 10.1016/j.ijbiomac.2016.11.095. Epub 2016 Nov 30.

DOI:10.1016/j.ijbiomac.2016.11.095
PMID:27914965
Abstract

Carrageenan is a natural polysaccharide extracted from edible red seaweeds of Rhodophycea class. It has been used as a viscosity increasing or gelling agent for prolonged and controlled drug release, food, pharmaceuticals and other industries. However, in spite of wide range of applications, carrageenan has some drawbacks and adverse effects on the biological systems, so its modifications with natural and synthetic polymers are carried out. This review article presents different sources and properties of carrageenans with special emphasis on natural polymer based carrageenan blends and composites and their applications in controlled drug delivery system, wound dressing and tissue engineering because of their biodegradability and biocompatibility, food industry as thickening/gelling materials, cosmeceuticals and making polyelectrolyte complexes.

摘要

角叉菜胶是一种从红藻纲可食用红海藻中提取的天然多糖。它已被用作增稠剂或胶凝剂,用于延长和控制药物释放、食品、制药和其他行业。然而,尽管角叉菜胶有广泛的应用,但它对生物系统有一些缺点和不良影响,因此人们对其进行了天然和合成聚合物的改性。这篇综述文章介绍了角叉菜胶的不同来源和特性,特别强调了基于天然聚合物的角叉菜胶共混物和复合材料,以及它们在控释给药系统、伤口敷料和组织工程中的应用,因为它们具有生物可降解性和生物相容性,在食品工业中作为增稠/胶凝材料,在药妆品中以及用于制备聚电解质复合物。

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