Bahçeci Semiha, Karaman Sait, Nacaroğlu Hikmet Tekin, Yazıcı Selçuk, Girit Saniye, Ünsal-Karkıner Şule, Can Demet
Department of Pediatrics, Dr. Behçet Uz Pediatric Hospital, İzmir, Turkey.
Department of Pediatrics, Balıkesir University Faculty of Medicine Balıkesir, Turkey.
Turk J Pediatr. 2016;58(1):19-26. doi: 10.24953/turkjped.2016.01.003.
Non-cystic fibrosis bronchiectasis again becomes a major health problem due to inappropriate antibiotic use and increasing frequency of protracted bacterial bronchitis. The aim was to determine the changes in etiology of bronchiectasis. Patients who admitted to Behçet Uz Children Hospital between 2005 and 2015 (n=110) were retrospectively examined. The etiology of bronchiectasis was detected as; primary ciliary dyskinesia 26.4%, protracted bacterial bronchitis 22.8%, primary immune deficiency 11.8%, bronchiolitis obliterans 8.2%, lung disease secondary to gastro-esophageal reflux 3.7%, foreign body aspiration 2.7%, tuberculosis %2.7, congenital malformation 1.8% and asthma 1.8%, respectively. In 15.4% of cases, etiology was not identified clearly. 91% of the patients were medically treated. In ten years, the frequency of asthma and tuberculosis in etiology had decreased but primary ciliary dyskinesia and primary immune deficiency had increased. Non-cystic fibrosis bronchiectasis can be followed up for a long time with medical treatment.
由于抗生素使用不当以及迁延性细菌性支气管炎发病率增加，非囊性纤维化支气管扩张再次成为一个主要的健康问题。目的是确定支气管扩张病因的变化。对2005年至2015年间入住贝切特·乌兹儿童医院的患者（n = 110）进行回顾性研究。检测到支气管扩张的病因分别为：原发性纤毛运动障碍26.4%、迁延性细菌性支气管炎22.8%、原发性免疫缺陷11.8%、闭塞性细支气管炎8.2%、胃食管反流继发肺部疾病3.7%、异物吸入2.7%、结核病2.7%、先天性畸形1.8%和哮喘1.8%。在15.4%的病例中，病因未明确。91%的患者接受了药物治疗。十年间，病因中哮喘和结核病的发病率有所下降，但原发性纤毛运动障碍和原发性免疫缺陷有所增加。非囊性纤维化支气管扩张可以通过药物治疗进行长期随访。
