Spielmanns Marc, Boeselt Tobias, Gloeckl Rainer, Klutsch Anja, Fischer Henrike, Polanski Henryk, Nell Christoph, Storre Jan H, Windisch Wolfram, Koczulla Andreas R
Medical Clinic and Pulmonary Rehabilitation in Leverkusen (April), Remigius Hospital, Leverkusen Opladen, Germany.
Faculty of Health, Department of Pneumology, University of Witten/Herdecke, Witten, Germany.
Respir Care. 2017 Mar;62(3):315-323. doi: 10.4187/respcare.05154. Epub 2016 Dec 6.
The objective of this study was to investigate the benefits of a low-volume out-patient whole-body vibration training (WBVT) program on exercise capacity in comparison with a calisthenics training program in subjects with COPD.
In this single-center randomized controlled trial, 29 subjects with mild to severe COPD were randomized to WBVT or to calisthenics training, including relaxation and breathing retraining in combination with calisthenics exercises. Both groups equally exercised for a duration of 3 months with 2 sessions of 30 min/week. Outcome parameters were 6-min walk distance (6MWD, primary outcome), 5-repetition sit-to-stand test, leg press peak force, Berg balance scale, St George Respiratory Questionnaire, and COPD assessment test.
Twenty-seven subjects completed the study (WBVT, = 14; calisthenics training program, = 13). Baseline characteristics between groups were comparable. Subjects in the WBVT group significantly improved median (interquartile range) 6MWD (+105 [45.5-133.5] m, = .001), sit-to-stand test (-2.3 [-3.1 to -1.3] s, = .001), peak force (28.7 [16.7-33.3] kg, = .001), and Berg balance scale (1.5 [0.0-4.0] points, = .055). Changes in 6MWD, sit-to-stand test, and leg press peak force were also found to be significantly different between groups in favor of the WBVT group. Only the between-group difference of the COPD assessment test score was in favor of the calisthenics training group ( = .02).
A low-volume WBVT program resulted in significantly and clinically relevant larger improvements in exercise capacity compared with calisthenics exercises in subjects with mild to severe COPD. (ClinicalTrials.gov registration DRKS9706.).
本研究的目的是调查与传统健身训练计划相比，低强度门诊全身振动训练（WBVT）计划对慢性阻塞性肺疾病（COPD）患者运动能力的益处。
在这项单中心随机对照试验中，29例轻至重度COPD患者被随机分为WBVT组或传统健身训练组，传统健身训练组包括放松和呼吸再训练以及传统健身练习。两组均每周进行2次，每次30分钟，共锻炼3个月。结果参数包括6分钟步行距离（6MWD，主要结果）、5次坐立试验、腿部推举峰值力量、伯格平衡量表、圣乔治呼吸问卷和慢性阻塞性肺疾病评估测试。
27例患者完成了研究（WBVT组14例；传统健身训练组13例）。两组间的基线特征具有可比性。WBVT组患者的6MWD中位数（四分位间距）显著改善（增加105 [45.5 - 133.5] m，P = .001）、坐立试验（减少2.3 [-3.1至 - 1.3] s，P = .001）、峰值力量（增加28.7 [16.7 - 33.3] kg，P = .001）和伯格平衡量表（增加1.5 [0.0 - 4.0]分，P = .055）。还发现两组间6MWD、坐立试验和腿部推举峰值力量的变化存在显著差异，有利于WBVT组。只有慢性阻塞性肺疾病评估测试评分的组间差异有利于传统健身训练组（P = .02）。
与传统健身练习相比，低强度WBVT计划在轻至重度COPD患者中能显著且在临床上带来更大的运动能力改善。（ClinicalTrials.gov注册号DRKS9706.）
