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[促红细胞生成素对长期保存的供血者血液形态功能特征的影响]

[Effect of erythropifadin on the morphofunctional characteristics of donor blood preserved for a long time].

作者信息

Belkin A L, Pendrak K A, Povzhitkova M S, Petrenko S V, Kovalishin Ia F

出版信息

Fiziol Zh (1978). 1989 Jul-Aug;35(4):15-9.

PMID:2792435
Abstract

Adenine- and riboxine-containing erythropifaden has been studied for possibility to be used for restoring a functional value of erythrocytes in conserved donor blood stored for 35-49 days. Energy supply and oxygen transport function of erythrocytes are shown to get normal and their morphological composition--to get considerably improved. Besides, osmotic resistance and deformability of erythrocytes insignificantly change while concentration of riboxine in blood and that of substances with average molecular mass remain considerably high. One of the ways to remove the above shortcomings is application of hemosorbents.

摘要

含腺嘌呤和核糖核苷的促红细胞生成素已被研究用于恢复保存35至49天的供血者血液中红细胞的功能价值的可能性。结果表明,红细胞的能量供应和氧运输功能恢复正常,其形态组成也有显著改善。此外,红细胞的渗透压抗性和可变形性变化不明显,而血液中核糖核苷和平均分子量物质的浓度仍相当高。消除上述缺点的方法之一是应用血液吸附剂。

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