Levy Y, Moskowitz M, Brook J G
Harefuah. 1989 Jun 1;116(11):581-2.
Minoxidil is a potent antihypertensive which is reserved for severe cases. A 58-year-old man admitted for evaluation of progressive dyspnea and peripheral edema had been taking Minoxidil, Normiten and Lasix for severe hypertension. Echocardiography disclosed a massive pericardial effusion but there were no signs of tamponade. Discontinuation of Minoxidil resulted in complete clearance of the pericardial fluid within 3 months. Awareness of this potentially fatal side-effect of Minoxidil is mandatory.
米诺地尔是一种强效降压药,仅用于重症病例。一名58岁男性因进行性呼吸困难和外周水肿入院评估,他一直在服用米诺地尔、诺米替恩和速尿治疗严重高血压。超声心动图显示大量心包积液,但无心脏压塞迹象。停用米诺地尔后,心包积液在3个月内完全清除。必须认识到米诺地尔这种潜在的致命副作用。