来自耳叶牛皮消茎的裂孕甾烷糖苷。
Seco-pregnane glycosides from the stems of Epigynum auritum.
作者信息
Gao Fei, Yao Yuan-Cheng, Wan Zong, Cai Sheng-Bao, Fan Jian, Zhao Tian-Rui, Cao Jian-Xin, Cheng Gui-Guang
机构信息
a Yunnan Institute of Food Safety , Kunming University of Science and Technology , Kunming , People's Republic of China.
出版信息
Nat Prod Res. 2017 May;31(9):1102-1105. doi: 10.1080/14786419.2016.1263852. Epub 2016 Dec 8.
Chemical investigation of the stems of Epigynum auritum led to the isolation and identification of a novel 16,17-seco pregnane glycoside, epigynoside D, along with other three known compounds (2-4). The structure of compound 1 was elucidated by means of spectroscopic analysis, including HRESIMS, 1D and 2D NMR experiments. All isolated compounds were tested for their in vitro cytotoxic, immunological and anti-acetylcholinesterase activities.
对耳叶牛皮消茎进行化学研究，从中分离并鉴定出一种新型的16,17-断孕甾烷糖苷——耳叶牛皮消苷D，以及其他三种已知化合物（2 - 4）。通过光谱分析，包括高分辨电喷雾电离质谱、一维和二维核磁共振实验，阐明了化合物1的结构。对所有分离出的化合物进行了体外细胞毒性、免疫活性和抗乙酰胆碱酯酶活性测试。
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