Liu Wendong, Jiang Libin, Jin Yulan, Yang Bentao, Lai Timothy Yy
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory.
Department of Pathology.
Onco Targets Ther. 2016 Oct 14;9:6333-6336. doi: 10.2147/OTT.S106842. eCollection 2016.
A 23-year-old male with intermittent visual loss in his left eye for 4 months was originally treated as optic neuritis elsewhere. Upon presentation to our hospital (Beijing Tongren Hospital), his left eye visual acuity was reduced to hand motion at face. The left eye ocular motility was limited in upgaze, downgaze, adduction, and abduction. Computed tomography and magnetic resonance imaging revealed lesions in the sphenoid and ethmoid sinuses, orbital apex and carvernous sinus invading adjacent extraocular muscles. Endoscopic ethmo-sphenoidostomy and debulking surgery was performed and histopathology of the specimen demonstrated alveolar rhabdomyosarcoma. Despite having treatment with a combination of orbital radiation therapy and systemic chemotherapy, the patient developed generalized metastasis with cachexia and the left eye became no light perception due to optic atrophy.
一名23岁男性，左眼间歇性视力丧失4个月，最初在其他地方被诊断为视神经炎。来我院（北京同仁医院）就诊时，其左眼视力降至眼前手动。左眼眼球运动在向上注视、向下注视、内收和外展时均受限。计算机断层扫描和磁共振成像显示蝶窦和筛窦、眶尖及海绵窦有病变，侵犯了相邻的眼外肌。进行了鼻内镜筛蝶窦开放术和减瘤手术，标本的组织病理学显示为肺泡横纹肌肉瘤。尽管接受了眼眶放射治疗和全身化疗联合治疗，患者仍出现全身转移并伴有恶病质，左眼因视神经萎缩而无光感。
