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人体中铯吸收与潴留的测量。

Measurements of Cs absorption and retention in man.

作者信息

Henrichs H, Paretzke H G, Voigt G, Berg D

机构信息

GSF--Institut für Strahlenschutz, Neuherberg, Federal Republic of Germany.

出版信息

Health Phys. 1989 Oct;57(4):571-8. doi: 10.1097/00004032-198910000-00008.

DOI:10.1097/00004032-198910000-00008
PMID:2793472
Abstract

One of the consequences of the Chernobyl reactor accident in 1986 was a comparatively high contamination of foodstuffs in Southern Federal Republic of Germany. In order to test radioecological models predicting the radiological consequences of such accidents, several thousand measurements were performed to determine Cs body burdens in members of the public. For the interpretation of these data and as a contribution to the improvement of the available database on the biokinetics of Cs isotopes in humans, we followed a small group of volunteers after their consumption of highly contaminated venison. Intakes, excretion rates and total body activities were measured during a period of more than 200 d. The data obtained were evaluated in terms of a compartment model to derive gastrointestinal uptakes, biological half-lives and dose conversion factors. The resulting uptake factors range from 65-90%, the half-lives of the long-term retention from 45 to 200 d. The majority of the resulting dose conversion factors lie below the values recommended by the ICRP, showing that the ICRP model is a reasonable and safe description of the Cs biokinetics in our study group, while the great variability of the results shows that it is not an accurate representation of the individual Cs retention.

摘要

1986年切尔诺贝利反应堆事故的后果之一是德意志联邦共和国南部的食品受到较高程度的污染。为了检验预测此类事故辐射后果的放射生态学模型,进行了数千次测量以确定公众成员体内的铯负荷。为了解释这些数据并为改进现有的关于铯同位素在人体内生物动力学的数据库做出贡献,我们追踪了一小群食用了高度污染鹿肉的志愿者。在超过200天的时间里测量了摄入量、排泄率和全身活度。根据隔室模型对获得的数据进行评估,以得出胃肠道摄取量、生物半衰期和剂量转换因子。所得摄取因子范围为65%至90%,长期滞留的半衰期为45至200天。所得剂量转换因子的大多数低于国际辐射防护委员会推荐的值,这表明国际辐射防护委员会的模型对我们研究组中铯的生物动力学是一种合理且安全的描述,而结果的巨大变异性表明它并不能准确代表个体铯的滞留情况。

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