Tikanmäki Marjaana, Tammelin Tuija, Kaseva Nina, Sipola-Leppänen Marika, Matinolli Hanna-Maria, Hakonen Harto, Ekelund Ulf, Eriksson Johan G, Järvelin Marjo-Riitta, Vääräsmäki Marja, Kajantie Eero
Department of Health, Chronic Disease Prevention Unit, National Institute for Health and Welfare, Oulu and Helsinki, Finland.
Institute of Health Sciences, University of Oulu, Oulu, Finland.
Pediatr Res. 2017 Apr;81(4):550-555. doi: 10.1038/pr.2016.262. Epub 2016 Dec 9.
Young adults born preterm have higher levels of cardio metabolic risk factors and they report less physical activity than their peers born at term. Physical activity provides important cardio metabolic health benefits. We hypothesized that objectively measured physical activity levels are lower and time spent sedentary is higher among preterm-born individuals compared with controls.
We studied unimpaired participants of the ESTER birth cohort study at age 23.3 y (SD: 1.2): 60 born early preterm (<34 wk), 108 late preterm (34-36 wk), and 178 at term (controls). Physical activity and sedentary time were measured by hip-worn accelerometer (ActiGraph).
As compared with controls' (mean physical activity, 303 counts per minute (cpm; SD 129)), physical activity was similar among adults born early preterm (mean difference = 21 cpm, 95% CI -61, 19) or late preterm (5 cpm, -27, 38). Time spent sedentary was also similar. Adjustments for early life confounders or current mediating characteristics did not change the results.
In contrast to our hypothesis, we found no difference in objectively measured physical activity or time spent sedentary between adults born preterm and at term. The previously reported differences may be limited to physical activity captured by self-report.
早产出生的年轻人具有更高水平的心血管代谢风险因素，且他们报告的身体活动比足月出生的同龄人少。身体活动对心血管代谢健康有重要益处。我们假设，与对照组相比，早产出生个体的客观测量身体活动水平较低，久坐时间较长。
我们在23.3岁（标准差：1.2）时研究了酯类出生队列研究中未受损的参与者：60例极早早产儿（<34周），108例晚期早产儿（34 - 36周），以及178例足月儿（对照组）。通过佩戴在臀部的加速度计（ActiGraph）测量身体活动和久坐时间。
与对照组（平均身体活动，每分钟303计数（cpm；标准差129））相比，极早早产出生的成年人（平均差异 = 21 cpm，95%置信区间 -61，19）或晚期早产出生的成年人（5 cpm，-27，38）的身体活动相似。久坐时间也相似。对早期生活混杂因素或当前中介特征进行调整后，结果未改变。
与我们的假设相反，我们发现早产出生和足月出生的成年人在客观测量的身体活动或久坐时间方面没有差异。先前报告的差异可能仅限于自我报告所记录的身体活动。
