Tikanmäki Marjaana, Kaseva Nina, Tammelin Tuija, Sipola-Leppänen Marika, Matinolli Hanna-Maria, Eriksson Johan G, Järvelin Marjo-Riitta, Vääräsmäki Marja, Kajantie Eero
Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Oulu, Helsinki, Finland; Institute of Health Sciences, University of Oulu, Oulu, Finland.
Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Oulu, Helsinki, Finland.
J Pediatr. 2017 Oct;189:135-142.e2. doi: 10.1016/j.jpeds.2017.06.068. Epub 2017 Jul 24.
To evaluate the amount of self-reported physical activity in young adults born prematurely compared with those born at term.
Unimpaired participants of the Preterm Birth Study (Preterm Birth and Early Life Programming of Adult Health and Disease) birth cohort study were studied at age 23.3 ± 1.2 (SD) years: 118 born early preterm (<34 weeks), 210 late preterm (34-36 weeks), and 311 born at term (≥37 weeks, controls). The participants completed a validated 30-item, 12-month physical activity questionnaire. The annual frequency and total volume of conditioning and nonconditioning leisure time physical activity and commuting physical activity were calculated and the data analyzed by means of linear regression.
Adults born early preterm reported a 31.5% (95% CI, 17.4-43.2) lower volume of leisure time physical activity (in metabolic equivalents [MET] h/year) and had a 2.0-fold increased OR (1.2-3.3) of being in the least active quintile than controls. Lower amounts of conditioning, nonconditioning, and commuting physical activity all contributed to the difference. In addition, early preterm participants undertook less vigorous physical activity (≥6 MET). No differences in physical activity were found between the late preterm and control groups. Adjustments for potential early life confounders and current mediating health characteristics did not change the results.
Young adults born early preterm engage less in leisure time physical activities than peers born at term. This finding may in part underlie the increased risk factors of cardiometabolic and other noncommunicable diseases in adults born preterm. Low physical activity is a risk factor for several noncommunicable diseases and amenable to prevention.
评估早产出生的年轻成年人与足月出生的年轻成年人自我报告的身体活动量。
对早产研究（早产与成人健康和疾病的早期生活编程）出生队列研究中未受损的参与者进行研究，研究对象年龄为23.3±1.2（标准差）岁：118例极早早产儿（<34周），210例晚期早产儿（34 - 36周），311例足月儿（≥37周，对照组）。参与者完成了一份经过验证的包含30个条目的12个月身体活动问卷。计算了休闲时间有条件和无条件身体活动以及通勤身体活动的年度频率和总量，并通过线性回归分析数据。
极早早产出生的成年人报告的休闲时间身体活动量（以代谢当量[MET]小时/年计）低31.5%（95%置信区间，17.4 - 43.2），且处于最不活跃五分位数的比值比（OR）比对照组增加了2.0倍（1.2 - 3.3）。有条件、无条件和通勤身体活动量较低均导致了这种差异。此外，极早早产参与者进行的剧烈身体活动（≥6 MET）较少。晚期早产儿和对照组之间在身体活动方面未发现差异。对潜在的早期生活混杂因素和当前中介健康特征进行调整后，结果未改变。
极早早产出生的年轻成年人在休闲时间进行的身体活动比足月出生的同龄人少。这一发现可能部分解释了早产出生的成年人患心脏代谢和其他非传染性疾病风险增加的原因。低身体活动是几种非传染性疾病的风险因素，且可预防。
