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用于纳米机器人应用的混合磁电纳米线:制造、磁电耦合和磁辅助体外靶向药物输送。

Hybrid Magnetoelectric Nanowires for Nanorobotic Applications: Fabrication, Magnetoelectric Coupling, and Magnetically Assisted In Vitro Targeted Drug Delivery.

机构信息

Multi-Scale Robotics Lab (MSRL), Institute of Robotics & Intelligent Systems (IRIS), ETH Zurich, Zurich, 8092, Switzerland.

Center for Nanophase Materials Sciences and Institute for Functional Imaging of Materials, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA.

出版信息

Adv Mater. 2017 Feb;29(8). doi: 10.1002/adma.201605458. Epub 2016 Dec 12.

Abstract

An FeGa@P(VDF-TrFE) wire-shaped magnetoelectric nanorobot is designed and fabricated to demonstrate a proof-of-concept integrated device, which features wireless locomotion and on-site triggered therapeutics with a single external power source (i.e., a magnetic field). The device can be precisely steered toward a targeted location wirelessly by rotating magnetic fields and perform on-demand magnetoelectrically assisted drug release to kill cancer cells.

摘要

设计并制作了一种 An FeGa@P(VDF-TrFE) 型纤维状磁电纳米机器人,以展示一种具有无线运动和现场触发治疗功能的集成设备,该设备仅使用单个外部电源(即磁场)。该设备可以通过旋转磁场精确地无线引导至目标位置,并按需进行磁电辅助药物释放以杀死癌细胞。

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