Mason Christopher, Dooley Nessa, Griffiths Mark
Barts Heart Centre, St Bartholomew's Hospital, London, UK.
National Heart & Lung Institute, Imperial College, London, UK.
Clin Med (Lond). 2016 Dec;16(Suppl 6):s66-s70. doi: 10.7861/clinmedicine.16-6-s66.
Acute respiratory distress syndrome is a common cause of acute respiratory failure that is underdiagnosed both inside and outside of intensive care units. Progression to the most severe forms of the syndrome confers a mortality rate greater than 40% and is associated with often severe functional disability and psychological sequelae in survivors. While there are no disease-modifying pharmacotherapies for the syndrome, this progression may be prevented through the institution of quality improvement measures that minimise iatrogenic injury associated with acute severe illness.
急性呼吸窘迫综合征是急性呼吸衰竭的常见病因,在重症监护病房内外均存在诊断不足的情况。该综合征进展为最严重形式时,死亡率超过40%,且幸存者常伴有严重的功能残疾和心理后遗症。虽然目前尚无针对该综合征的疾病改善性药物治疗方法,但通过实施质量改进措施,尽量减少与急性重症疾病相关的医源性损伤,或许可以预防这种进展。