Barts Heart Centre, St Bartholomew's Hospital, London, UK.
National Heart & Lung Institute, Imperial College, London, UK.
Clin Med (Lond). 2017 Oct;17(5):439-443. doi: 10.7861/clinmedicine.17-5-439.
Acute respiratory distress syndrome is a common cause of acute respiratory failure that is underdiagnosed both inside and outside of intensive care units. Progression to the most severe forms of the syndrome confers a mortality rate greater than 40% and is associated with often severe functional disability and psychological sequelae in survivors. While there are no disease-modifying pharmacotherapies for the syndrome, this progression may be prevented through the institution of quality improvement measures that minimise iatrogenic injury associated with acute severe illness.
急性呼吸窘迫综合征是急性呼吸衰竭的常见原因,在重症监护病房内外均存在诊断不足的情况。该综合征发展为最严重形式的死亡率超过 40%,并与幸存者经常发生严重的功能障碍和心理后遗症相关。虽然目前尚无针对该综合征的疾病修饰性药物治疗方法,但通过实施质量改进措施,可预防这种进展,这些措施可最大限度地减少与急性重症疾病相关的医源性损伤。