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肝外伤的治疗:手术治疗还是保守治疗。

Treatment of Liver Trauma: Operative or Conservative Management.

作者信息

Bernardo Carmen Garcia, Fuster Josep, Bombuy Ernest, Sanchez Santiago, Ferrer Joana, Loera Marco Antonio, Marti Josep, Fondevila Constantino, Zavala Elizabet, Garcia-Valdecasas Juan Carlos

机构信息

Department of Surgery. Hepatic Surgery and Liver Transplant Unit, IMDIM. CIBERHED,IDIBAPS, Spain.

Intensive Care Unit. Department of Anesthesiology. Hospital Clinic, University of Barcelona, Barcelona, Spain.

出版信息

Gastroenterology Res. 2010 Feb;3(1):9-18. doi: 10.4021/gr2010.02.165w. Epub 2010 Jan 20.

Abstract

BACKGROUND

The liver is one of the most frequently damaged organs when abdominal trauma occurs. Currently, a conservative management constitutes the treatment of choice in patients with hemodynamic stability. The aim of this study is to evaluate the results of an operative and conservative management of 143 patients with liver injury treated in a single institution.

METHODS

A retrospective study of the patients admitted with the diagnosis of liver trauma was performed from 1992-2008. The patients were classified according to the intention to treatment: Group I, operative management; Group II, conservative management. Variables analyzed included demographic data, injury classification, associated lesions, surgical treatment, transfusions, morbi-mortality, and hospital stay. We established two periods (1992-1999; 2000-2008) in order to compare diagnosis and management.

RESULTS

A total of 143 patients were analyzed. Thirty-one percent correspond to severe injuries. Conservative treatment was followed in 60.8 % with surgery undertaken in 14.9 % of patients from this group due to failure of conservative treatment. Immediate surgery was carried out in 38.2 %. Total mortality was 14 %. Morbidity (35.7-38.5 %) in the group of immediate surgery and failure of conservative management is similar, but not in mortality (28.6-15.4 %). In the second group (2000-2008) there are more patients with conservative treatment, with a low percentage of failure of this treatment and morbi-mortality.

CONCLUSIONS

Conservative treatment is an adequate treatment in a great number of patients. Failure of conservative treatment did not show a higher incidence of complications or mortality but it should be performed in centers with experienced surgeons.

摘要

背景

腹部创伤发生时,肝脏是最常受损的器官之一。目前,对于血流动力学稳定的患者,保守治疗是首选的治疗方法。本研究的目的是评估在单一机构接受治疗的143例肝损伤患者手术治疗和保守治疗的结果。

方法

对1992年至2008年诊断为肝创伤的住院患者进行回顾性研究。根据治疗意向将患者分为两组:第一组,手术治疗;第二组,保守治疗。分析的变量包括人口统计学数据、损伤分级、相关损伤、手术治疗、输血情况、发病率和死亡率以及住院时间。我们设定了两个时间段(1992 - 1999年;2000 - 2008年)以比较诊断和治疗情况。

结果

共分析了143例患者。31%为重伤。60.8%的患者接受了保守治疗,其中14.9%的患者因保守治疗失败而接受了手术。38.2%的患者立即接受了手术。总死亡率为14%。立即手术组和保守治疗失败组的发病率(35.7 - 38.5%)相似,但死亡率不同(28.6 - 15.4%)。在第二组(2000 - 2008年),接受保守治疗的患者更多,该治疗失败率以及发病率和死亡率较低。

结论

保守治疗对大量患者来说是一种合适的治疗方法。保守治疗失败并未显示出更高的并发症发生率或死亡率,但应在有经验丰富外科医生的中心进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/144c/5139834/ff1afc88696c/gr-03-009-g001.jpg

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