Lin Lu, Wang Dan, Chen Si-Hong, Wang Dun-Jia, Yin Guo-Dong
College of Chemistry and Chemical Engineering, Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University, Huangshi 435002, China.
College of Chemistry and Chemical Engineering, Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University, Huangshi 435002, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2017 Mar 5;174:272-278. doi: 10.1016/j.saa.2016.11.053. Epub 2016 Dec 2.
A novel fluorescent chemosensor based on the oxadiazole, 2-(2-hydroxyphenyl)-5-(4-methoxyphenyl)-1,3,4-oxadiazole, was designed and synthesized. The interaction of the oxadiazole with different metal ions had been investigated through UV-vis absorption and fluorescence spectra in 9:1 (v/v) ethanol-water (pH=7.0) solution. The oxadiazole showed a pronounced fluorescence enhancement at 430nm upon addition of Zn in aqueous solution, whereas it had no apparent interference from other metal ions. The results indicated that the oxadiazole possessed high selectivity and sensitivity to Zn ion. The stoichiometric ratio between the oxadiazole and Zn ion was calculated to be 2:1 by Job plot experiment, meanwhile their binding modes was confirmed by H NMR and mass spectrometry. Their association constant was determined to be 1.95×10M and the detection limit for Zn ion was 6.14×10mol/L.
设计并合成了一种基于恶二唑的新型荧光化学传感器，即2-(2-羟基苯基)-5-(4-甲氧基苯基)-1,3,4-恶二唑。通过紫外可见吸收光谱和荧光光谱，研究了该恶二唑在9:1（v/v）乙醇-水（pH = 7.0）溶液中与不同金属离子的相互作用。在水溶液中加入锌后，该恶二唑在430nm处荧光显著增强，而其他金属离子无明显干扰。结果表明，该恶二唑对锌离子具有高选择性和高灵敏度。通过Job曲线实验计算得出恶二唑与锌离子的化学计量比为2:1，同时通过核磁共振氢谱和质谱确定了它们的结合模式。测定其缔合常数为1.95×10M，锌离子的检测限为6.14×10mol/L。
