Craig B W, Brown R, Everhart J
Human Performance Laboratory, Ball State University, Muncie, IN 47306.
Mech Ageing Dev. 1989 Aug;49(2):159-69. doi: 10.1016/0047-6374(89)90099-7.
We observed the response of serum growth hormone (GH) and testosterone (T) to a progressive resistance strength training program. Basal levels (after a 12-h fast) of GH and T were measured in young (23 years) and elderly (63 years) subjects before and after a 12-week training program. The response of GH and T to an acute bout of exercise was also measured. The exercise training, which involved all the major muscle groups, was conducted on Nautilus equipment and required 45-60 min for completion. The subjects completed three sets of lifts with 8-10 Reps/set. Blood was drawn from an anticubital vein, centrifuged (1169 g) for 15 min and the serum frozen for later analysis. The acute exercise blood samples were taken immediately before and after the exercise and at 15 min post-exercise during week 1 and 12. The hormone assay was carried out with radioimmunoassay kits for GH and T. The basal level of GH increased by 44.9% in the young and by only 3% in the elderly but neither change was significant. In response to a single exercise session GH levels in the young went from 0.85 +/- 0.13 to 4.19 +/- 1.45 ng/ml before training and from 1.45 +/- 0.11 to 8.61 +/- 2.55 after training. Each response was significant (P less than 0.05) as were the pre-post differences (P less than 0.001). In the elderly the response was not as great, values increasing from 1.00 +/- 0.09 to 2.92 +/- 0.65 ng/ml before training and from 1.50 +/- 0.06 to 3.43 +/- 0.64 ng/ml after training were recorded. These differences represented significant increases (P less than 0.05) but did not demonstrate pre- to post-changes. Basal levels of T decreased in both groups, but were not significant. The T response to an acute bout of exercise was not significant but did increase in both age groups. In conclusion, the data presented here indicate that strength training can induce growth hormone and testosterone release, regardless of age, but that the elderly response does not equal that of the young.
我们观察了血清生长激素（GH）和睾酮（T）对渐进性抗阻力量训练计划的反应。在一项为期12周的训练计划前后，分别测量了年轻（23岁）和老年（63岁）受试者的GH和T的基础水平（禁食12小时后）。还测量了GH和T对一次急性运动的反应。运动训练涉及所有主要肌肉群，在诺德士健身器材上进行，完成训练需要45 - 60分钟。受试者完成三组举重练习，每组8 - 10次重复。从肘前静脉采血，以1169g离心15分钟，将血清冷冻以备后续分析。急性运动血样在第1周和第12周运动前、运动后即刻以及运动后15分钟采集。使用针对GH和T的放射免疫分析试剂盒进行激素检测。年轻受试者的GH基础水平增加了44.9%，老年受试者仅增加了3%，但两者变化均无统计学意义。对于年轻受试者，单次运动训练前GH水平从0.85±0.13 ng/ml升至4.19±1.45 ng/ml，训练后从1.45±0.11 ng/ml升至8.61±2.55 ng/ml。每次反应均有统计学意义（P < 0.05），训练前后差异也有统计学意义（P < 0.001）。在老年受试者中，反应没那么大，训练前水平从1.00±0.09 ng/ml升至2.92±0.65 ng/ml，训练后从1.50±0.06 ng/ml升至3.43±0.64 ng/ml。这些差异表示有显著增加（P < 0.05），但未显示出训练前后的变化。两组受试者的T基础水平均下降，但无统计学意义。T对一次急性运动的反应无统计学意义，但在两个年龄组中均有增加。总之，此处呈现的数据表明，力量训练可诱导生长激素和睾酮释放，与年龄无关，但老年受试者的反应不如年轻受试者。
