Katalambula Leonard K, Ntwenya Julius Edward, Ngoma Twalib, Buza Joram, Mpolya Emmanuel, Mtumwa Abdallah H, Petrucka Pammla
School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania; Department of Public Health, University of Dodoma, Dodoma, Tanzania.
Department of Public Health, University of Dodoma, Dodoma, Tanzania.
J Cancer Epidemiol. 2016;2016:3769829. doi: 10.1155/2016/3769829. Epub 2016 Nov 14.
. Colorectal cancer (CRC) is a growing public health concern with increasing rates in countries with previously known low incidence. This study determined pattern and distribution of CRC in Tanzania and identified hot spots in case distribution. . A retrospective chart audit reviewed hospital registers and patient files from two national institutions. Descriptive statistics, Chi square () tests, and regression analyses were employed and augmented by data visualization to display risk variable differences. . CRC cases increased sixfold in the last decade in Tanzania. There was a 1.5% decrease in incidences levels of rectal cancer and 2% increase for colon cancer every year from 2005 to 2015. Nearly half of patients listed Dar es Salaam as their primary residence. CRC was equally distributed between males (50.06%) and females (49.94%), although gender likelihood of diagnosis type (i.e., rectal or colon) was significantly different ( = 0.027). More than 60% of patients were between 40 and 69 years. . Age ( = 0.0183) and time ( = 0.004) but not gender ( = 0.0864) were significantly associated with rectal cancer in a retrospective study in Tanzania. Gender ( = 0.0405), age ( = 0.0015), and time ( = 0.0075) were all significantly associated with colon cancer in this study. This retrospective study found that colon cancer is more prevalent among males at a relatively younger age than rectal cancer. Further, our study showed that although more patients were diagnosed with rectal cancer, the trend has shown that colon cancer is increasing at a faster rate.
. 结直肠癌(CRC)是一个日益受到公众关注的健康问题,在以前发病率较低的国家,其发病率也在上升。本研究确定了坦桑尼亚结直肠癌的发病模式和分布情况,并确定了病例分布的热点地区。. 一项回顾性图表审核研究回顾了两家国家级机构的医院登记册和患者档案。采用了描述性统计、卡方()检验和回归分析,并通过数据可视化进行补充,以展示风险变量的差异。. 在过去十年中,坦桑尼亚的结直肠癌病例增加了六倍。从2005年到2015年,直肠癌发病率每年下降1.5%,结肠癌发病率每年上升2%。近一半的患者将达累斯萨拉姆列为其主要居住地。结直肠癌在男性(50.06%)和女性(49.94%)中的分布相当,尽管诊断类型(即直肠癌或结肠癌)的性别可能性存在显著差异( = 0.027)。超过60%的患者年龄在40至69岁之间。. 在坦桑尼亚的一项回顾性研究中,年龄( = 0.0183)和时间( = 0.004)与直肠癌显著相关,但性别( = 0.0864)与之无关。在本研究中,性别( = 0.0405)、年龄( = 0.0015)和时间( = 0.0075)均与结肠癌显著相关。这项回顾性研究发现,与直肠癌相比,结肠癌在相对年轻的男性中更为普遍。此外,我们的研究表明,尽管被诊断为直肠癌的患者更多,但趋势显示结肠癌的增长速度更快。