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[儿童军团病]

[Legionnaires' disease in children].

作者信息

Raos M, Bela-Klancir S, Koncul I, Sanjek M

出版信息

Lijec Vjesn. 1989 Jun-Jul;111(6-7):202-5.

PMID:2796576
Abstract

During the first nine months of 1987, the bacteriological and virological tests as well as the indirect fluorescence test to Legionella pneumophila were performed in 40 children with bronchopneumonia (one- or both-sided) or pleuropneumonia and in 10 children with protracted bronchitis. In a 15 month old boy we have proved (by titer dynamics) the infection with Legionella pneumophila serotype 5, and in a 15 month old girl and in a 16 month old boy serotype 1. The infection was sporadic and the possible source of infection was unknown. The course of the disease was not wasting and the infection was accompanied with fever. The patients had an increased sedimentation rate of red cells and leukocytosis. All the other laboratory findings were within normal limits. In seven children seropositiveness 1:256 to Legionella pneumophila serotype 1, and in two children an increased titer to adenovirus was proved. The high titer to Legionella pneumophila in those seven children indicates an early contact with the causal agent. The patients were successfully treated with cefuroxim, which is not the drug of choice. Infection due to Legionella pneumophila in children does not exhibit a clinical or laboratory characteristic features that differ from those of the other respiratory diseases in children. It means that Legionnaires' disease in children with intact immunity is not the wasting illness. We stress the importance of using serologic examination to Legionella pneumophila as a routine procedure in the aetiological diagnosis of respiratory diseases in children.

摘要

1987年的前九个月,对40例支气管肺炎(单侧或双侧)或胸膜肺炎患儿以及10例迁延性支气管炎患儿进行了细菌学、病毒学检测以及嗜肺军团菌间接荧光试验。在一名15个月大的男孩身上(通过滴度动态变化)证实感染了嗜肺军团菌血清型5,在一名15个月大的女孩和一名16个月大的男孩身上证实感染了血清型1。感染为散发性,感染源不明。疾病过程未出现消瘦,且伴有发热。患者红细胞沉降率升高,白细胞增多。所有其他实验室检查结果均在正常范围内。在7名儿童中证实对嗜肺军团菌血清型1呈1:256血清阳性,在2名儿童中证实腺病毒滴度升高。那7名儿童中嗜肺军团菌的高滴度表明早期接触过病原体。患者用头孢呋辛成功治愈,而头孢呋辛并非首选药物。儿童嗜肺军团菌感染未表现出与儿童其他呼吸道疾病不同的临床或实验室特征。这意味着免疫功能正常的儿童患军团病并非消耗性疾病。我们强调在儿童呼吸道疾病的病因诊断中,将嗜肺军团菌血清学检查作为常规程序的重要性。

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1
[Legionnaires' disease in children].[儿童军团病]
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