Zhou Yan, Chan Chi-Fai, Kwong Daniel W J, Law Ga-Lai, Cobb Steven, Wong Wai-Kwok, Wong Ka-Leung
Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, China.
Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Hung Hum, Hong Kong SAR, China.
Chem Commun (Camb). 2017 Jan 3;53(3):557-560. doi: 10.1039/c6cc09246b.
We have synthesized a bifunctional erbium-porphyrin tumor imaging and PDT agent (Er-R3) that is capable of killing bladder cancer cells via its selective binding to the integrin αβ isoform overexpressed on the cell membrane.
我们合成了一种双功能铒-卟啉肿瘤成像及光动力治疗剂（Er-R3），它能够通过选择性结合细胞膜上过度表达的整合素αβ异构体来杀死膀胱癌细胞。
