微生物组发出信息的原地踏步。

Ticking in Place for the Microbiome to Message Out.

机构信息

Merck Research Laboratory Cambridge Exploratory Science Center, Cambridge, MA 02141, USA.

Department of Genetics and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.

出版信息

Cell Metab. 2016 Dec 13;24(6):775-777. doi: 10.1016/j.cmet.2016.11.015.

DOI:10.1016/j.cmet.2016.11.015

PMID:27974176

Abstract

In a recent issue of Cell, Thaiss et al. (2016) report that gut microbiota exhibit diurnal rhythmicity in biogeographical localization and metabolomics during the 24 hr light-dark cycle. This oscillation, together with the host circadian clock, co-regulates the colonic and hepatic epigenome and transcriptome.

摘要

在最近一期的《细胞》杂志上，Thaiss 等人（2016 年）报道称，肠道微生物群在 24 小时光-暗周期中表现出生物地理学定位和代谢组学的昼夜节律性。这种振荡与宿主生物钟共同调节结肠和肝脏的表观基因组和转录组。