Ogawa Atsushi, Murashige Yuta, Tabuchi Junichiro, Omatsu Taiki
Proteo-Science Center, Ehime University, 3 Bunkyo-cho, Matsuyama, Ehime 790-8577, Japan.
Mol Biosyst. 2017 Jan 31;13(2):314-319. doi: 10.1039/c6mb00748a.
We have rationally constructed a novel regulation-type of artificial riboswitch that ligand-dose dependently upregulates translation initiation mediated by a 3' cap-independent translation element (3' CITE) with no major hybridization switches in a plant expression system (wheat germ extract).
我们已经合理构建了一种新型调控型人工核糖开关，在植物表达系统（小麦胚芽提取物）中，它能以配体剂量依赖性方式上调由3'帽独立翻译元件（3' CITE）介导的翻译起始，且不存在主要的杂交开关。
