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蛋白质组生物信息学导论

An Introduction to Proteome Bioinformatics.

作者信息

Keerthikumar Shivakumar

机构信息

Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia.

出版信息

Methods Mol Biol. 2017;1549:1-3. doi: 10.1007/978-1-4939-6740-7_1.

Abstract

High-throughput techniques are indispensable for aiding basic and translational research. Among them, recent advances in proteomics techniques have allowed biomedical researchers to characterize the proteome of multiple organisms. This remarkable advancement have been well complemented by proteome bioinformatics methods and tools. Proteome bioinformatics refers to the study and application of informatics in the field of proteomics. This chapter provides an overview of computational strategies, methods, and techniques reported in this book for bioinformatics analysis of protein data. An outline of many bioinformatics tools, databases, and proteomic techniques described in each of the chapters is given here.

摘要

高通量技术对于辅助基础研究和转化研究不可或缺。其中,蛋白质组学技术的最新进展使生物医学研究人员能够对多种生物体的蛋白质组进行表征。蛋白质组生物信息学方法和工具对这一显著进展起到了很好的补充作用。蛋白质组生物信息学是指信息学在蛋白质组学领域的研究与应用。本章概述了本书中报道的用于蛋白质数据生物信息学分析的计算策略、方法和技术。这里给出了各章节中描述的许多生物信息学工具、数据库和蛋白质组学技术的概述。

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