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临床医生的胎儿监测与预测:极低出生体重儿随机临床试验中的观察结果

Fetal monitoring and predictions by clinicians: observations during a randomized clinical trial in very low birth weight infants.

作者信息

Larson E B, van Belle G, Shy K K, Luthy D A, Strickland D, Hughes J P

机构信息

Department of Medicine, University of Washington School of Medicine, Seattle.

出版信息

Obstet Gynecol. 1989 Oct;74(4):584-9.

PMID:2797635
Abstract

Predictions about perinatal outcome in very low birth weight infants were studied in a randomized clinical trial of electronic fetal monitoring and periodic auscultation to assess the effect of diagnostic monitoring information on clinicians' ability to predict perinatal outcomes. The only predictions consistently correct before monitoring information was available were those regarding infant survival (88% correct, kappa [kappa] = 0.40, P less than .001 for the electronic fetal monitoring group; 80% correct, kappa = 0.35, P less than .01 for the periodic auscultation group). After monitoring, predictions of 5-minute Apgar scores and arterial cord pH were significantly more accurate, and clinicians' confidence in their predictions increased significantly in both the electronic fetal monitoring and the auscultation groups. Predictions of 5-minute Apgar scores were significantly more accurate in the electronic fetal monitoring group (92% correct, kappa = 0.80) than in the periodic auscultation group (61% correct, kappa = 0.28) (Z difference = 3.04; P less than .01). We conclude that clinicians gain information during intrapartum monitoring that generally leads to improved predictions and increased confidence in predictions. In this study, they made more accurate predictions about 5-minute Apgar scores with electronic fetal monitoring, suggesting that electronic fetal monitoring may provide better information about neonatal well-being than does periodic auscultation. Improved information, as measured by clinical predictions, is probably highly valued by patients and clinicians and may be an important determinant of acceptance of this diagnostic technology.

摘要

在一项关于电子胎儿监护与定期听诊的随机临床试验中,研究了极低出生体重儿围产期结局的预测情况,以评估诊断性监护信息对临床医生预测围产期结局能力的影响。在获得监护信息之前,唯一始终正确的预测是关于婴儿存活情况(电子胎儿监护组预测正确率为88%,kappa值=0.40,P<0.001;定期听诊组预测正确率为80%,kappa值=0.35,P<0.01)。监护后,对5分钟阿氏评分和脐动脉pH值的预测明显更准确,并且电子胎儿监护组和听诊组的临床医生对其预测的信心均显著增加。电子胎儿监护组对5分钟阿氏评分的预测(正确率92%,kappa值=0.80)明显比定期听诊组(正确率61%,kappa值=0.28)更准确(Z差异=3.04;P<0.01)。我们得出结论,临床医生在产时监护过程中获得的信息通常会使预测得到改善且对预测的信心增强。在本研究中,他们通过电子胎儿监护对5分钟阿氏评分做出了更准确的预测,这表明电子胎儿监护可能比定期听诊能提供关于新生儿健康状况的更好信息。通过临床预测衡量的信息改善可能受到患者和临床医生的高度重视,并且可能是接受这项诊断技术的一个重要决定因素。

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