Kiprenskiĭ Iu V, Luk'ianov M V, Kurenkova L G, Vasilenko T V
Ortop Travmatol Protez. 1989 Jun(6):33-6.
The authors have studied the dynamic changes of metabolic processes and the functional and the structural preservation of the muscles under the influence of heat ischemia (18-21 degrees C) on 29 amputated posterior extremities of 21 adult dogs of the both sexes. It has been shown that direct muscle excitability disappears 5 hours after the influence of heat ischemia, although after 6 hours of observation the values of the metabolic processes in the muscles made 35-40% of the basic level. The character of the changes in the muscle excitability gives an idea of the duration of action of heat ischemia and the preservation of vitality of the amputated extremity only up to the moment of its complete disappearance. The final irreversible ultrastructural lesions of the overwhelming majority of the myocytes appear during the period of 6 to 8 hours of action of heat ischemia.
作者对21只成年雌雄犬的29条截肢后肢，研究了热缺血（18 - 21摄氏度）影响下肌肉代谢过程的动态变化以及肌肉的功能和结构保存情况。结果表明，热缺血作用5小时后肌肉直接兴奋性消失，尽管观察6小时后肌肉中代谢过程的值为基础水平的35 - 40%。肌肉兴奋性变化的特征可让人了解热缺血的作用持续时间以及截肢肢体仅在其完全消失前的活力保存情况。绝大多数肌细胞的最终不可逆超微结构损伤出现在热缺血作用6至8小时期间。
