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1型糖尿病男性患者中，蛋白尿与 copeptin 浓度升高有关：来自T1D交换生物样本库的简要报告。

Albuminuria is associated with greater copeptin concentrations in men with type 1 diabetes: A brief report from the T1D exchange Biobank.

作者信息

Bjornstad Petter, Johnson Richard J, Snell-Bergeon Janet K, Pyle Laura, Davis Asa, Foster Nicole, Cherney David Z, Maahs David M

机构信息

Department of Pediatric Endocrinology, University of Colorado School of Medicine, Aurora, CO; Barbara Davis Center for Diabetes, University of Colorado Denver, Aurora, CO.

Department of Nephrology, University of Colorado Denver, Aurora, CO.

出版信息

J Diabetes Complications. 2017 Feb;31(2):387-389. doi: 10.1016/j.jdiacomp.2016.11.015. Epub 2016 Dec 7.

DOI:10.1016/j.jdiacomp.2016.11.015
PMID:27979439
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5303164/
Abstract

Vasopressin exerts important cardio-renal effects, but remains problematic to measure. Copeptin is a more stable peptide derived from the same precursor molecule. In this case-control study from the Type 1 Diabetes Exchange (T1DX) Biobank registry, men with T1D and albuminuria had greater copeptin concentrations than men with normoalbuminuria.

摘要

血管加压素具有重要的心脏和肾脏作用，但测量起来仍存在问题。 copeptin是一种源自同一前体分子的更稳定的肽。在这项来自1型糖尿病交换（T1DX）生物样本库登记处的病例对照研究中，患有1型糖尿病和蛋白尿的男性的copeptin浓度高于正常白蛋白尿的男性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222f/5303164/3ebedad6c2e3/nihms834682f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222f/5303164/3ebedad6c2e3/nihms834682f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/222f/5303164/3ebedad6c2e3/nihms834682f1.jpg

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