Reisch J S, Tyson J E, Mize S G
Academic Computing Services, University of Texas Southwestern Medical Center, Dallas 75235-9066.
Pediatrics. 1989 Nov;84(5):815-27.
Physicians are often faced with conflicting recommendations from therapeutic studies. An evaluation form is proposed to facilitate the evaluation of the quality of therapeutic studies and the resulting treatment or management recommendations in any area of medicine. Twelve major topics for evaluation include sample size determination, randomization, selection of control group(s), "blinding," and support for treatment recommendations. Emphasis is placed on study design and performance rather than data analysis. Thirty-four primary criteria based on accepted research standards are designated as most important, and examples from the literature are provided to illustrate their use. The form provides a comprehensive set of well-accepted standards of research in a format that encourages detailed, consistent, and thoughtful evaluation of therapeutic studies. The evaluation form is recommended as a tool for physicians who wish to develop and exercise skill in evaluating therapeutic studies.
医生常常面临治疗研究中相互矛盾的建议。本文提出一种评估表，以促进对治疗研究质量以及由此得出的医学任何领域的治疗或管理建议的评估。十二个主要评估主题包括样本量确定、随机化、对照组选择、“盲法”以及对治疗建议的支持。重点在于研究设计和实施而非数据分析。基于公认研究标准的三十四个主要标准被指定为最重要的标准，并提供文献中的示例来说明其用法。该评估表以一种鼓励对治疗研究进行详细、一致且深入评估的格式，提供了一套全面且广为接受的研究标准。对于希望培养和锻炼评估治疗研究技能的医生而言，推荐将该评估表作为一种工具。
