8年间从一名囊性纤维化患者痰液中分离出的40株铜绿假单胞菌临床菌株的基因组序列草图
Draft Genome Sequences of 40 Pseudomonas aeruginosa Clinical Strains Isolated from the Sputum of a Single Cystic Fibrosis Patient Over an 8-Year Period.
作者信息
Bianconi Irene, D'Arcangelo Silvia, Benedet Mattia, Bailey Kate E, Esposito Alfonso, Piffer Elena, Mariotto Alex, Baldo Ermanno, Dinnella Grazia, Gualdi Paola, Schinella Michele, Donati Claudio, Jousson Olivier
机构信息
Centre for Integrative Biology (CIBIO), University of Trento, Trento, Italy.
Trentino Cystic Fibrosis Support Centre, Rovereto Hospital, Trento, Italy.
出版信息
Genome Announc. 2016 Dec 15;4(6):e01205-16. doi: 10.1128/genomeA.01205-16.
Abstract
We report draft genome sequences of 40 Pseudomonas aeruginosa strains, isolated from the sputum of a single cystic fibrosis patient over eight years. Analyses indicated a correlation between multidrug-resistant phenotypes and population structure. Our data provide new insights into the mechanisms leading to acquisition of antibiotic resistance in P. aeruginosa.
摘要
我们报告了从一名囊性纤维化患者八年间痰液中分离出的40株铜绿假单胞菌菌株的基因组序列草图。分析表明多重耐药表型与群体结构之间存在相关性。我们的数据为铜绿假单胞菌获得抗生素耐药性的机制提供了新的见解。
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