Winston A Blessed, Das Adhikari Debasis, Das Saibal, Vazhudhi Kaysina, Kumar Aniket, Shanthi Fx Margaret, Agarwal Indira
a Department of Pharmacology and Clinical Pharmacology , Christian Medical College , Vellore , Tamil Nadu , India.
b Paediatric Emergency, Department of Paediatrics , Christian Medical College , Vellore , Tamil Nadu , India.
Hosp Pract (1995). 2017 Feb;45(1):21-27. doi: 10.1080/21548331.2017.1273734. Epub 2016 Dec 27.
This study was performed to determine the incidence, demographic distribution, types and outcomes across various drug poisonings among children from south India.
This retrospective study included children less than 16 years who presented to the Pediatric Emergency Department with drug poisoning from the 1st of October 2004 to the 30th of September 2013.
Out of the total 997 poisoning cases, 366 (36.71%) were contributed by drugs; mainly antiepileptics, central nervous system depressants, psychotropics, analgesic-antipyretics and natural drugs. Males and children of < 5 years were mostly affected. Although many children developed complications and required intensive care unit admissions, the total mortality rate was less than 1%. The incidence of drug poisoning showed a decreasing trend over the last 4 years.
This study for the first time gives an elaborative insight into pediatric drug poisoning over a nine-year period from a Pediatric Emergency Department tertiary care center in south India.
本研究旨在确定印度南部儿童各类药物中毒的发生率、人口统计学分布、类型及结局。
这项回顾性研究纳入了2004年10月1日至2013年9月30日期间因药物中毒就诊于儿科急诊科的16岁以下儿童。
在总共997例中毒病例中，366例（36.71%）由药物引起；主要是抗癫痫药、中枢神经系统抑制剂、精神药物、解热镇痛药和天然药物。男性及5岁以下儿童受影响最为严重。尽管许多儿童出现了并发症并需要入住重症监护病房，但总死亡率低于1%。药物中毒的发生率在过去4年呈下降趋势。
本研究首次从印度南部一家儿科急诊科三级护理中心对9年期间的儿科药物中毒情况进行了详尽的剖析。
