Das Adhikari Debasis, Das Saibal, Winston A Blessed, Vazhudhi Kaysina, Kumar Aniket, Shanthi Fx Margaret, Agarwal Indira
a Paediatric Emergency, Department of Paediatrics , Christian Medical College , Vellore , Tamil Nadu , India.
b Department of Pharmacology and Clinical Pharmacology , Christian Medical College , Vellore , Tamil Nadu , India.
Hosp Pract (1995). 2017 Apr;45(2):39-45. doi: 10.1080/21548331.2017.1303326. Epub 2017 Mar 24.
This retrospective study was performed to determine the incidence, demographic distribution, types and outcomes across various non-drug related poisonings among children attending a tertiary care center in south India.
All children from 0-16 years who presented to the Paediatric Emergency Department, Christian Medical College, Vellore with non-drug related poisoning from October 2004 to September 2013 were included.
Out of the total 997 cases of poisoning, 629 (63.1%) cases were contributed by chemicals and plants: mainly hydrocarbons (kerosene) 309 (49.1%); organophosphates 72 (11.5%); corrosive acids and alkalis 57 (9.1%); insecticides 51 (8.1%); and plant poisons 20 (3.2%). Males (62.79%) and children < 5 years (77.42%) were mostly affected. Although many children developed complications requiring intensive care unit admissions, the total mortality was only 9 (1.4%). The incidence of poisoning showed a decreasing trend over the last 4 years.
This study for the first time gives an elaborative insight on non-drug related pediatric poisoning from a tertiary care center in south India for almost a decade.
本回顾性研究旨在确定印度南部一家三级护理中心收治的儿童各类非药物相关中毒的发生率、人口统计学分布、类型及结局。
纳入2004年10月至2013年9月期间因非药物相关中毒就诊于韦洛尔基督教医学院儿科急诊科的所有0至16岁儿童。
在总共997例中毒病例中，629例（63.1%）由化学品和植物引起：主要是碳氢化合物（煤油）309例（49.1%）；有机磷72例（11.5%）；腐蚀性酸和碱57例（9.1%）；杀虫剂51例（8.1%）；植物毒物20例（3.2%）。男性（62.79%）和5岁以下儿童（77.42%）受影响最为严重。尽管许多儿童出现了需要入住重症监护病房的并发症，但总死亡率仅为9例（1.4%）。中毒发生率在过去4年呈下降趋势。
本研究首次对印度南部一家三级护理中心近十年来的非药物相关儿童中毒情况进行了详尽的深入分析。
