Koh Shao Hui, Tan Kian Hua Barry, Ganapathy Sashikumar
Department of Emergency Medicine, Sengkang General Hospital, Singapore.
Department of Children's Emergency, KK Women's and Children's Hospital, Singapore.
Singapore Med J. 2018 May;59(5):247-250. doi: 10.11622/smedj.2018053.
Paediatric poisoning accounts for 1% of daily emergency department presentations. The aim of this study was to review the characteristics and outcomes of paediatric patients who presented with drug overdose over a five-year period.
We performed a retrospective review of paediatric poisoning cases at KK Women's and Children's Hospital (KKH), the largest children's public hospital in Singapore, from 1 January 2009 to 31 December 2013.
A total of 1,208 cases of poisoning were seen in KKH's Department of Children's Emergency during the study period. The gender distribution was about equal, with a slight male predominance. The majority of the poisoning cases were accidental. Slightly more than half of the intentional ingestions were of paracetamol and the majority were female patients belonging to the 12-16 year age group. The bulk of poisonings occurred in children aged 1-4 via the oral route, slightly more than half of the oral ingestions consisted of oral medications and a sizeable portion were of household liquids. Mothballs and silica gels accounted for almost a quarter of the solid household products ingested. Slightly less than half of the patients required admission and only a small portion of the admitted patients required intensive or high dependency care.
The prognosis of paediatric patients who presented with poisoning in our study was good, with a short median length of stay for those admitted and no fatalities being reported across the span of five years.
儿科中毒病例占每日急诊科就诊病例的1%。本研究的目的是回顾五年期间出现药物过量的儿科患者的特征及转归。
我们对新加坡最大的儿童公立医院——KK妇女儿童医院(KKH)2009年1月1日至2013年12月31日期间的儿科中毒病例进行了回顾性研究。
在研究期间,KKH儿童急诊科共诊治了1208例中毒病例。性别分布大致相等,男性略占优势。大多数中毒病例为意外中毒。略超过半数的故意摄入病例为对乙酰氨基酚中毒,且大多数为12至16岁年龄组的女性患者。大部分中毒发生在1至4岁儿童,经口服途径摄入,略超过半数的口服摄入物为口服药物,相当一部分为家用液体。卫生球和硅胶占摄入的固体家用产品的近四分之一。略少于半数的患者需要住院治疗,且只有一小部分住院患者需要重症或高度依赖护理。
在我们的研究中,出现中毒的儿科患者预后良好,住院患者的中位住院时间较短,且在五年期间未报告死亡病例。