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[一种用于治疗轻度精神病理性抑郁症的曲唑酮缓释新制剂。一项对照研究]

[A new sustained-release formulation of trazodone for treatment of minor psychopathological depression. A controlled study].

作者信息

Piccione M

出版信息

Riv Eur Sci Med Farmacol. 1989 Apr;11(2):169-74.

PMID:2799002
Abstract

In a controlled study the activity and tolerance of two formulations of trazodone (traditional and controlled-release) were compared in a group of 30 geriatric patients with minor anxious-depressive manifestations. The results showed a better activity with the controlled-release formulation (a single dose administered in the evening) on sleep disturbances as far as their effects on the psychopathological picture is concerned or on tolerance.

摘要

在一项对照研究中，对30名有轻微焦虑抑郁症状的老年患者比较了两种曲唑酮制剂（传统制剂和控释制剂）的活性和耐受性。结果显示，就对精神病理状况的影响或耐受性而言，控释制剂（晚上单次给药）对睡眠障碍有更好的活性。

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