Micallef Darren, Micallef Sarah, Schembri-Wismayer Pierre, Calleja-Agius Jean
Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, Tal-Qroqq, Msida, Malta.
J Turk Ger Gynecol Assoc. 2016 Dec 1;17(4):214-223. doi: 10.5152/jtgga.2016.15200. eCollection 2016.
Recent evidence shows that commonly prescribed drugs, such as non-steroidal anti-inflammatory drugs (NSAIDs), metformin, and statins, may have beneficial roles in the primary chemoprevention of breast cancer. Therefore, these drugs could potentially be used in addition to the hormonal drugs currently used for this purpose (namely, selective estrogen receptor modulators and aromatase inhibitors) due to their alternative mechanisms of action.
最近的证据表明，常用药物，如非甾体抗炎药（NSAIDs）、二甲双胍和他汀类药物，可能在乳腺癌的一级化学预防中发挥有益作用。因此，由于其不同的作用机制，这些药物有可能在目前用于此目的的激素药物（即选择性雌激素受体调节剂和芳香化酶抑制剂）之外联合使用。
