农村地区印度 HIV 阳性妇女的遵医行为与身心健康之间的关系。
Relationships Among Adherence and Physical and Mental Health Among Women Living with HIV in Rural India.
机构信息
School of Nursing, University of California, Room 2-250, Factor Building, Los Angeles, CA, 90095-1702, USA.
Center for AIDS Prevention Studies, University of California, San Francisco, USA.
出版信息
AIDS Behav. 2018 Mar;22(3):867-876. doi: 10.1007/s10461-016-1631-3.
We conducted a cross-sectional examination of the physical and psychological factors related to ART adherence among a sample of 400 women living with HIV/AIDS in rural India. Interviewer-administered measures assessed adherence, internalized stigma, depressive symptoms, quality of life, food insecurity, health history and sociodemographic information. CD4 counts were measured using blood collected at screening. Findings revealed that adherence to ART was generally low, with 94% of women taking 50% or less of prescribed medication in past month. Multivariate analyses showed a non-linear association between numbers of self-reported opportunistic infections (OIs) in past 6 months (p = 0.016) and adherence, with adherence decreasing with each additional OI for 0-5 OIs. For those reporting more than 5 OIs, the association reversed direction, with increasing OIs beyond 5 associated with greater adherence.
我们对印度农村地区 400 名感染艾滋病毒/艾滋病的女性进行了横断面检查，以研究与抗逆转录病毒治疗（ART）依从性相关的身体和心理因素。访谈者管理的措施评估了依从性、内化污名、抑郁症状、生活质量、食物不安全、健康史和社会人口统计学信息。通过在筛查时采集的血液来测量 CD4 计数。研究结果显示，ART 的依从性普遍较低，94%的女性在过去一个月内服用的药物不到处方的 50%。多变量分析显示，过去 6 个月内自我报告的机会性感染（OI）次数（p=0.016）与依从性之间存在非线性关联，0-5 次 OI 时依从性随每次 OI 的增加而下降。对于报告有超过 5 次 OI 的人，这种关联的方向相反，超过 5 次 OI 时，OI 增加与更高的依从性相关。
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