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全球成人 HIV 感染者常见心理健康障碍系统评价

Global Systematic Review of Common Mental Health Disorders in Adults Living with HIV.

机构信息

Division of Liaison Psychiatry, Department of Psychiatry and Mental health, University of Cape Town, Anzio Road Observatory, Cape Town, 7925, South Africa.

Faculty of Health Sciences, Penisula Medical School, University of Plymouth, Plymouth, UK.

出版信息

Curr HIV/AIDS Rep. 2021 Dec;18(6):569-580. doi: 10.1007/s11904-021-00583-w. Epub 2021 Nov 18.

Abstract

PURPOSE OF THE REVIEW

By reviewing the most recent common mental health disorders (CMHD) studies in people living with HIV (PLWH) (2018-2020), this review discusses the prevalence of CMHD, factors associated with CMHD in PLWH, mental health in PLWH from vulnerable groups, the impact of CMHD on HIV disease progression and adherence to antiretroviral therapy and the efficacy of different treatment approaches.

RECENT FINDINGS

After screening for eligibility 142 studies were included in the final systematic review. Only 27% of studies were conducted in Sub-Saharan Africa, which carries the highest burn of HIV disease globally. Despite the well-established increased risk of CMHD in PLWH, the current prevalence remains high, with studies reporting 28%-62% of PLWH having mental health symptoms.

CONCLUSION

Despite the significant challenges that CMHDs present to successful HIV treatment, there are many mental health treatments and interventions which can improve outcomes in PLWH and opportunities to task-shift and integrate mental health care with HIV care.

摘要

目的综述

通过对 2018-2020 年间患有 HIV 的人群(PLWH)中最常见的精神健康障碍(CMHD)研究进行回顾,本综述讨论了 CMHD 的流行率、与 PLWH 中 CMHD 相关的因素、来自弱势群体的 PLWH 的心理健康状况、CMHD 对 HIV 疾病进展和抗逆转录病毒治疗依从性的影响,以及不同治疗方法的疗效。

新发现

经过资格筛选,共有 142 项研究被纳入最终的系统综述。仅有 27%的研究是在撒哈拉以南非洲进行的,该地区是全球 HIV 疾病负担最重的地区。尽管 PLWH 中 CMHD 的风险明显增加,但目前的流行率仍然很高,研究报告称 28%-62%的 PLWH 存在心理健康症状。

结论

尽管 CMHD 对成功治疗 HIV 带来了重大挑战,但有许多心理健康治疗和干预措施可以改善 PLWH 的预后,并且有机会将精神保健与 HIV 保健进行任务分工和整合。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9754/8600343/df6a932a82f3/11904_2021_583_Fig1_HTML.jpg

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