Zhao Lihui, Mu Jie, Du Ping, Wang Hailing, Mao Yiran, Xu Yong, Xin Xiaojie, Zang Fenglin
Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute and Hospital, Huan-Hu-Xi Road, Ti-Yuan-Bei, He Xi District, Tianjin, 300060, China.
Department of Pathology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Pediatr Surg Int. 2017 Mar;33(3):347-353. doi: 10.1007/s00383-016-4037-4. Epub 2016 Dec 18.
Ultrasound-guided biopsy technique with the large-core needle has widely been applied in the diagnosis of adult abdominopelvic cavity, thyroid, and neck tumors. There are few reports on ultrasound-guided biopsy using large-core needle in pediatric abdominopelvic cavity tumors. This study was to evaluate the ultrasound features and the diagnostic value of ultrasound-guided core needle biopsy for pediatric neuroblastic tumors.
The pediatric patients with neuroblastic tumor that underwent ultrasound examination and ultrasound-guided core needle biopsy from January 2009 to November 2015 were reviewed. A minimum of two cores in each case was obtained. The biopsy results were confirmed by subsequent surgical histopathology. The ultrasound features and the diagnostic accuracy of ultrasound-guided core needle biopsy were evaluated.
Eighty-three patients were enrolled into the study. Conventional ultrasound examination showed irregular hypoechoic or mixed echo masses and calcification and liquefied necrosis. The diagnostic accuracy of ultrasound-guided core needle biopsy was 96.4% (80/83). Three cases were misdiagnosed because of inadequate tissue sample. No serious complication, infection, or needle track seeding occurred.
Ultrasound-guided core needle biopsy seems to be an accurate, minimally invasive, and safe diagnostic method of pediatric neuroblastic tumor.
超声引导下粗针活检技术已广泛应用于成人腹腔盆腔、甲状腺及颈部肿瘤的诊断。关于超声引导下粗针活检在小儿腹腔盆腔肿瘤中的应用报道较少。本研究旨在评估小儿神经母细胞瘤的超声特征及超声引导下粗针活检的诊断价值。
回顾性分析2009年1月至2015年11月期间接受超声检查及超声引导下粗针活检的小儿神经母细胞瘤患者。每例至少获取两条组织条。活检结果经后续手术病理证实。评估超声特征及超声引导下粗针活检的诊断准确性。
83例患者纳入研究。常规超声检查显示不规则低回声或混合回声肿块及钙化、液化坏死。超声引导下粗针活检的诊断准确性为96.4%（80/83）。3例因组织样本不足而误诊。未发生严重并发症、感染或针道种植。
超声引导下粗针活检似乎是小儿神经母细胞瘤准确、微创且安全的诊断方法。
