Kishore R, Sankar T Bavani, Anandi A, Nedunchezhian S, Murugan Valarmathy
Institute of General Surgery, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, 600003 Tamilnadu India.
Institute of General Surgery, Rajiv Gandhi Government General Hospital, Chennai, 600003 Tamilnadu India.
Indian J Surg. 2016 Oct;78(5):356-363. doi: 10.1007/s12262-016-1481-2. Epub 2016 May 16.
Perforators are those which connect the superficial and deep venous system either directly to main veins or indirectly through the muscular and soleal venous plexus. The emergence of minimally invasive techniques like ambulatory phlebectomy (AP) and foam sclerotherapy (FS) has led to increasing interest about the appropriate therapy for the treatment of isolated perforator incompetence. There have been no studies which have compared the effectiveness of these in-office procedures in isolated perforator incompetence due to the low prevalence of cases. The primary goal of this study is to compare the clinical parameters (return to normal activity, primary symptom relief), functional parameters (procedure time, change in disease severity, course of venous ulcer), and duplex parameters (recurrence in treated veins, complete occlusion of treated veins) in the management of leg varicosities having isolated primary perforator incompetence by ambulatory phlebectomy and duplex guided foam sclerotherapy. Though the procedure time was shorter with FS than AP, the other parameters of primary symptom relief such as change in disease severity, faster healing of venous ulcer, complete occlusion of treated veins in follow-up duplex examination, and lower recurrence of treated veins are better with AP than FS. In conclusion, the interruption of perforators is effective in decreasing the symptoms of chronic venous insufficiency and for the rapid healing of ulcers. The interruption of the incompetent perforating veins appears to be essential to decrease ambulatory venous hypertension. It is apparent from this study that ambulatory phlebectomy stands distinct with enormous benefits and serves as a superior alternative to foam sclerotherapy in treating patients with isolated perforator incompetence.
穿通静脉是那些将浅静脉系统和深静脉系统直接与主要静脉相连或通过肌肉和比目鱼肌静脉丛间接相连的静脉。诸如门诊静脉切除术(AP)和泡沫硬化疗法(FS)等微创技术的出现,引发了人们对治疗单纯性穿通静脉功能不全的适当疗法的兴趣日益浓厚。由于病例发生率较低,尚无研究比较这些门诊手术治疗单纯性穿通静脉功能不全的有效性。本研究的主要目的是比较门诊静脉切除术和双功超声引导下泡沫硬化疗法在治疗单纯性原发性穿通静脉功能不全的下肢静脉曲张时的临床参数(恢复正常活动、主要症状缓解)、功能参数(手术时间、疾病严重程度变化、静脉溃疡病程)和双功超声参数(治疗静脉复发、治疗静脉完全闭塞)。虽然FS的手术时间比AP短,但AP在主要症状缓解的其他参数方面,如疾病严重程度变化、静脉溃疡愈合更快、随访双功超声检查中治疗静脉完全闭塞以及治疗静脉复发率更低等方面均优于FS。总之,阻断穿通静脉可有效减轻慢性静脉功能不全的症状并促进溃疡快速愈合。阻断功能不全的穿通静脉似乎对于降低动态静脉高压至关重要。从本研究可以明显看出,门诊静脉切除术具有显著优势,在治疗单纯性穿通静脉功能不全的患者时是优于泡沫硬化疗法的选择。