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静脉剥除术与硬化疗法治疗静脉曲张患者的比较研究。

Phlebectomy versus Sclerotherapy in Varicose Vein Patients: A Comparative Study.

机构信息

Dr SM Parvez Ahmed, Assistant Professor, Department of Vascular Surgery, National Institute of Cardiovascular Disease (NICVD), Dhaka, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2023 Jul;32(3):743-748.

Abstract

Varicose veins are part of the spectrum of chronic venous disease and include spider telangiectasias, reticular veins, and true varicosities. It may present without advanced signs of chronic venous insufficiency. Sclerotherapy is a treatment choice for patients with varicose veins of lower extremity; it uses the intravenous injection of chemical drugs to achieve the goal of inflammatory occlusion. Phlebectomy, a minimally invasive procedure usually used for higher diameter of varicose veins at the surface of the skin. Objective of the study was to compare the outcome of Phlebectomy and Sclerotherapy in varicose vein patients. It was a quasi experimental study was conducted in the Department of Vascular Surgery in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period of June 2019 to May 2020. Patients admitted with varicose vein and varicosity of the lower limbs with valves and perforator incompetence in the Department of Vascular Surgery, BSMMU, Dhaka, Bangladesh. During this period 60 patients were selected purposive randomly. Patients were divided to 30 patients were treated with Phlebectomy (Group I) 30 patients were treated with Sclerotherapy (Group II). Data were collected according to the pre-designed semi-structured data collection sheet. After editing data analysis were carried out by using the Statistical Package for Social Science (SPSS) version 22.0 Windows software. This study shows average age 40.73±15.50 years in Phlebectomy (Group I) and 38.43±11.08 years in Sclerotherapy (Group II). Males are more commonly involved than females between two groups which was 76.7% in Phlebectomy (Group I) and 70.0% in Sclerotherapy (Group II). The change CEAP improved to 93.3% in patients who underwent phlebectomy when compared to 83.3% in patients who underwent sclerotherapy. During the follow-up with duplex at treated veins showed 93.3% complete occlusion of treated veins in the phlebectomy group, while only 70.0% of the patients in the sclerotherapy group showed evidence of complete occlusion. In phlebectomy group recurrence of leg varicosities were found 6.7% of the patients, while 26.7% of the patients in the sclerotherapy group. The difference was statistically significant between two groups (p=0.038). This study shows phlebectomy to be much better option than sclerotherapy for the treatment of varicose veins and hence can be used routinely. Both phlebectomy and sclerotherapy not only revealed minimal time taken for return to normal activity but also proved to be safer with regard to complications.

摘要

静脉曲张是慢性静脉疾病的范畴之一,包括蜘蛛状毛细血管扩张、网状静脉和真性静脉曲张。它可能在没有慢性静脉功能不全的晚期征象的情况下出现。硬化疗法是下肢静脉曲张患者的一种治疗选择;它使用静脉内注射化学药物来达到炎症闭塞的目的。静脉切除术是一种微创程序,通常用于皮肤表面直径较大的静脉曲张。本研究的目的是比较静脉切除术和硬化疗法在静脉曲张患者中的疗效。这是一项在孟加拉国达卡的班加班杜谢赫·穆吉布医科大学(BSMMU)血管外科进行的准实验研究。2019 年 6 月至 2020 年 5 月期间,在该部门收治了下肢静脉曲张和静脉扩张伴瓣膜和穿孔功能不全的患者。在此期间,共选择了 60 名患者进行随机抽样。将患者分为 30 名接受静脉切除术(I 组)和 30 名接受硬化疗法(II 组)。根据预先设计的半结构式数据收集表收集数据。编辑后,使用社会科学统计软件包(SPSS)版本 22.0 窗口软件进行数据分析。本研究显示,静脉切除术(I 组)的平均年龄为 40.73±15.50 岁,硬化疗法(II 组)的平均年龄为 38.43±11.08 岁。两组中男性比女性更常见,静脉切除术(I 组)为 76.7%,硬化疗法(II 组)为 70.0%。与接受硬化疗法的患者相比,接受静脉切除术的患者的 CEAP 评分改善至 93.3%。在接受治疗的静脉进行随访时,静脉切除术组有 93.3%的治疗静脉完全闭塞,而硬化疗法组只有 70.0%的患者显示完全闭塞的证据。在静脉切除术组中,有 6.7%的患者出现腿部静脉曲张复发,而硬化疗法组中则有 26.7%的患者出现复发。两组间差异有统计学意义(p=0.038)。本研究表明,与硬化疗法相比,静脉切除术是治疗静脉曲张的更好选择,因此可以常规使用。静脉切除术和硬化疗法不仅在恢复正常活动所需的时间上都显示出最小的时间,而且在并发症方面也被证明更安全。

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