Lekovic Danijela, Miljic Predrag, Dmitrovic Aleksandar, Thachil Jecko
Clinic for Hematology, Clinical Center of Serbia, Belgrade, Serbia; Medical Faculty, University of Belgrade, Belgrade, Serbia.
Clinic of Obstetrics and Gynecology, Clinical Center Serbia, Belgrade, Serbia.
Blood Rev. 2017 May;31(3):151-157. doi: 10.1016/j.blre.2016.12.001. Epub 2016 Dec 15.
Women are increasingly encouraged to participate in making decisions about hormone replacement therapy (HRT). In postmenopausal women with severe vasomotor symptoms, HRT can significantly improve the quality of life. However, the use of HRT may also increase the risk of venous thromboembolism (VTE), the risk which depends of both treatment-related and patient-related factors. This review summarizes some important points about the selection of the safest hormonal replacement modality in women with a history of VTE and management of VTE risks in postmenopausal women wishing to take HRT.
女性越来越多地被鼓励参与激素替代疗法（HRT）的决策。对于有严重血管舒缩症状的绝经后女性，HRT可显著改善生活质量。然而，使用HRT也可能增加静脉血栓栓塞（VTE）的风险，这一风险取决于治疗相关因素和患者相关因素。本综述总结了一些关于有VTE病史的女性选择最安全激素替代方式以及希望接受HRT的绝经后女性VTE风险管理的要点。
