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老年患者的游离皮瓣手术:110例年龄≥70岁患者的经验。

Free flap surgery in the elderly: Experience with 110 cases aged ≥70 years.

作者信息

Sierakowski A, Nawar A, Parker M, Mathur B

机构信息

St Andrew's Centre for Plastic Surgery and Burns, Chelmsford, UK.

St Andrew's Centre for Plastic Surgery and Burns, Chelmsford, UK.

出版信息

J Plast Reconstr Aesthet Surg. 2017 Feb;70(2):189-195. doi: 10.1016/j.bjps.2016.11.008. Epub 2016 Nov 24.

Abstract

We report our experience with free tissue transfer in the elderly based on a retrospective review of patients aged ≥70 years who underwent surgery during a 7-year period. A total of 110 free tissue transfers in 104 patients, with a mean age of 78 years (range: 70-92 years), were identified for inclusion. The demographic and operative variables and postoperative medical and surgical complications were analyzed. Sixty-four of the 110 procedures encountered at least one complication. Medical complications were observed in 25 cases and were predominantly pulmonary, whereas surgical complications occurred in 54 cases in addition to one perioperative death. Successful free tissue transfer was achieved in 105 of the 110 flaps. There was no statistically significant difference in the rate of postoperative complications between patients aged 70-79 years and those aged ≥80 years. Anesthetic time was a statistically significant predictor of postoperative medical complications (odds ratio 1.345, 95% confidence interval 1.117-1.663, P = 0.001). Preoperative comorbidity status, graded according to the ACE-27 index, was a statistically significant predictor of flap recipient site complications. Free tissue transfer may be performed in aging patients with a high degree of technical success and low operative mortality. Chronological age alone should not be used as a criterion when evaluating a patient for free tissue transfer. The patient's premorbid status should be carefully assessed. To minimize postoperative medical complications, duration of general anesthesia should be kept to a minimum.

摘要

我们通过对70岁及以上患者在7年期间接受手术的回顾性研究,报告了我们在老年患者中进行游离组织移植的经验。共确定纳入104例患者的110次游离组织移植,平均年龄78岁(范围:70 - 92岁)。分析了人口统计学和手术变量以及术后内科和外科并发症。110例手术中有64例至少出现一种并发症。25例出现内科并发症,主要为肺部并发症,54例出现外科并发症,另有1例围手术期死亡。110个皮瓣中有105个成功进行了游离组织移植。70 - 79岁患者与80岁及以上患者术后并发症发生率无统计学显著差异。麻醉时间是术后内科并发症的统计学显著预测因素(优势比1.345,95%置信区间1.117 - 1.663,P = 0.001)。根据ACE - 27指数分级的术前合并症状态是皮瓣受区并发症的统计学显著预测因素。游离组织移植在老年患者中技术成功率高且手术死亡率低。在评估患者是否适合进行游离组织移植时,不应仅以实际年龄作为标准。应仔细评估患者的病前状态。为尽量减少术后内科并发症,应将全身麻醉时间保持在最短。

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