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Back to the Future: Glomerular Hyperfiltration and the Diabetic Kidney.

作者信息

Tuttle Katherine R

机构信息

Providence Medical Research Center, Providence Health Care and Nephrology Division, Department of Medicine, Kidney Research Institute and Institute of Translational Health Sciences, University of Washington, Spokane, WA

出版信息

Diabetes. 2017 Jan;66(1):14-16. doi: 10.2337/dbi16-0056.

DOI:10.2337/dbi16-0056
PMID:27999101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5204314/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db7f/5204314/d5477e018cfd/dbi160056f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db7f/5204314/d5477e018cfd/dbi160056f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db7f/5204314/d5477e018cfd/dbi160056f1.jpg

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Back to the Future: Glomerular Hyperfiltration and the Diabetic Kidney.《回到未来：肾小球高滤过与糖尿病肾病》
Diabetes. 2017 Jan;66(1):14-16. doi: 10.2337/dbi16-0056.
2
Abnormalities of glomerular eicosanoid metabolism in states of glomerular hyperfiltration.肾小球高滤过状态下肾小球类花生酸代谢异常。
Adv Exp Med Biol. 1989;259:275-304. doi: 10.1007/978-1-4684-5700-1_12.
3
Primary proximal tubule hyperreabsorption and impaired tubular transport counterregulation determine glomerular hyperfiltration in diabetes: a modeling analysis.原发性近端肾小管重吸收增加和肾小管转运代偿调节受损决定糖尿病中的肾小球高滤过：一项建模分析。
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4
[Pathogenicity of glomerular hyperfiltration, a question of glomerular tolerance?].[肾小球高滤过的致病性，是肾小球耐受性的问题？]
Z Gesamte Inn Med. 1990 Apr 15;45(8):210-4.
5
[Hyperfiltration].
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Kidney function in early diabetes: the tubular hypothesis of glomerular filtration.早期糖尿病中的肾功能：肾小球滤过的肾小管假说
Am J Physiol Renal Physiol. 2004 Jan;286(1):F8-15. doi: 10.1152/ajprenal.00208.2003.
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The role of glomerular hyperfiltration in the initiation and progression of diabetic nephropathy.肾小球高滤过在糖尿病肾病发生及进展中的作用。
Acta Endocrinol Suppl (Copenh). 1981;242:7-10.
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L-Citrulline, but not L-arginine, prevents diabetes mellitus-induced glomerular hyperfiltration and proteinuria in rat.L-瓜氨酸，而不是 L-精氨酸，可预防糖尿病大鼠肾小球高滤过和蛋白尿。
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Twenty years of hyperfiltration without diabetic-type glomerulosclerosis.二十年的超滤而无糖尿病型肾小球硬化症。
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Can rodent models of diabetic kidney disease clarify the significance of early hyperfiltration?: recognizing clinical and experimental uncertainties.糖尿病肾病的啮齿动物模型能否阐明早期超滤的意义？：认识临床和实验中的不确定性。
Clin Sci (Lond). 2008 Jan;114(2):109-18. doi: 10.1042/CS20070088.

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本文引用的文献

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Renal and Systemic Effects of Calorie Restriction in Patients With Type 2 Diabetes With Abdominal Obesity: A Randomized Controlled Trial.热量限制对伴有腹型肥胖的2型糖尿病患者的肾脏及全身影响：一项随机对照试验
Diabetes. 2017 Jan;66(1):75-86. doi: 10.2337/db16-0607. Epub 2016 Sep 15.
2
Immunity and inflammation in diabetic kidney disease: translating mechanisms to biomarkers and treatment targets.糖尿病肾病中的免疫与炎症：将机制转化为生物标志物和治疗靶点。
Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F716-F731. doi: 10.1152/ajprenal.00314.2016. Epub 2016 Aug 24.
3
Sodium Glucose Cotransporter 2 Inhibitors in the Treatment of Diabetes Mellitus: Cardiovascular and Kidney Effects, Potential Mechanisms, and Clinical Applications.
实验大鼠中，钠-葡萄糖协同转运蛋白2抑制后近端肾小管增殖和延长的诱导作用。
J Diabetes Investig. 2025 Jul;16(7):1232-1242. doi: 10.1111/jdi.70043. Epub 2025 Apr 22.
4
Combination therapy: an upcoming paradigm to improve kidney and cardiovascular outcomes in chronic kidney disease.联合治疗：改善慢性肾脏病肾脏和心血管结局的一种新兴模式。
Nephrol Dial Transplant. 2025 Feb 5;40(Supplement_1):i3-i17. doi: 10.1093/ndt/gfae212.
5
Diagnostic and prognostic value of triglyceride glucose index: a comprehensive evaluation of meta-analysis.甘油三酯-葡萄糖指数的诊断和预后价值：荟萃分析的综合评价。
Cardiovasc Diabetol. 2024 Aug 23;23(1):310. doi: 10.1186/s12933-024-02392-y.
6
Novel Biomarkers for the diagnosis of diabetic nephropathy.用于诊断糖尿病肾病的新型生物标志物。
Caspian J Intern Med. 2024 Summer;15(3):382-391. doi: 10.22088/cjim.15.3.382.
7
Exploring the Causal Effects of Gut Microbiota on Diabetic Nephropathy: A Two-Sample Mendelian Randomization Study.探索肠道微生物群对糖尿病肾病的因果效应：一项两样本孟德尔随机化研究。
Comb Chem High Throughput Screen. 2025;28(6):1026-1038. doi: 10.2174/0113862073311197240425073859.
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Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.新型糖尿病肾病治疗药物的分子靶点：肾脏保护的新时代。
Int J Mol Sci. 2024 Apr 3;25(7):3969. doi: 10.3390/ijms25073969.
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Int J Mol Sci. 2024 Mar 7;25(6):3086. doi: 10.3390/ijms25063086.
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Front Endocrinol (Lausanne). 2024 Feb 14;15:1336123. doi: 10.3389/fendo.2024.1336123. eCollection 2024.
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New therapies for diabetic kidney disease.糖尿病肾病的新疗法。
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