Alavi Seyed Mohammad, Alavi Leila
Health Research Institute, Infectious and Tropical Disease Research Center, Joundishapur University of Medical Sciences, Ahvaz, Iran.
Food and Drug Deputy, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Caspian J Intern Med. 2016 Fall;7(4):233-241.
Human toxoplasmosis is an important zoonotic infection worldwide which is caused by the intracellular parasite (T.gondii). The aim of this study was to review briefly the general aspects of toxoplasma infection in in Iranian health system network.
We searched published toxoplasmosis related articles in English databases including Science Direct, Pub Med, Scopus, Google Scholar, Magiran, Iran Medex, Iran Doc and Scientific Information Database (SID) for toxoplasmosis.
Out of 1267 articles from the English and Persian databases search, 40 articles were suitable with our research objectives and so were selected for the study. It is estimated that at least a third of the world human population is infected with T.gondii, suggesting it as one of the most common parasitic infections through the world. Maternal infection during pregnancy may affect dangerous outcome for the fetus, or even cause intrauterine death. Reactivation of a previous infection in immunocompromised patient such as drug induced, AIDS and organ transplantation can cause life-threating central nervous system infection. Ocular toxoplasmosis is one of the most important causes of blindness, especially in individuals with a deficient immune system.
According to the increasing burden of toxoplasmosis on human health, the findings of this study highlight the appropriate preventive measures, diagnosis, and management of this disease.
人类弓形虫病是一种在全球范围内重要的人畜共患感染病，由细胞内寄生虫（刚地弓形虫）引起。本研究的目的是简要回顾伊朗卫生系统网络中弓形虫感染的一般情况。
我们在包括科学Direct、PubMed、Scopus、谷歌学术、Magiran、伊朗Medex、伊朗Doc和科学信息数据库（SID）在内的英文数据库中搜索已发表的与弓形虫病相关的文章。
在从英文和波斯文数据库搜索的1267篇文章中，有40篇符合我们的研究目标，因此被选入本研究。据估计，世界上至少三分之一的人口感染了刚地弓形虫，这表明它是全球最常见的寄生虫感染之一。孕期母亲感染可能会影响胎儿的危险结局，甚至导致宫内死亡。免疫功能低下患者（如药物诱导、艾滋病和器官移植患者）先前感染的复发可导致危及生命的中枢神经系统感染。眼部弓形虫病是失明的最重要原因之一，尤其是在免疫系统缺陷的个体中。
鉴于弓形虫病对人类健康的负担日益加重，本研究结果强调了对该疾病采取适当的预防措施、诊断和管理。
