Ebrahim Zadeh A, Bamedi T, Etemadi S, Shahrakipour M, Saryazdipour Kh
Department of Mycology and Parasitology, Tropical and Infectious Diseases Research Center,Zahedan University of Medical Sciences, Zahedan, Iran.
PhD Studentin Medical Parasitology, Department ofMedical Parasitology, School of Public Health, TehranUniversityof Medical Sciences,Tehran, Iran.
Iran J Ped Hematol Oncol. 2014;4(1):22-5. Epub 2014 Feb 20.
Toxoplasma Gondi is an obligate intracellular protozoan parasite that is one of the most important protozoa of blood and tissue. The medical importance of this parasite is considered from two aspects of congenital defects and opportunities among those with congenital immune deficiency. Depending on the mode of transmission through blood and the risk of infection to Toxoplasma Gondi in hemodialysis patients, this serological study was conducted on Iranian population.
This case-control study was conducted on 37 patients that underwent regular hemodialysis that 21 were male and 16 were female, and the mean age of them was 17.52±4.10 years (rages 13-22 years). Thirty-seven healthy individuals were chosen as control group. All samples were tested by using of ELISA kits with two methods of IgG-ELISA and IgM-ELISA. Finally obtained data was analysis by SPSS software.
The results of this study revealed high prevalence of toxoplasmosis among hemodialysis patients. Other findings indicate that 21 out of 37 patients in the case group were positive for anti-Toxoplasma Gondi IgG in case group while in control group just 11 individuals were positive that was a statistically significant difference(p <0.05 ).
because of the high prevalence of toxoplasmosis among hemodialysis patients, identification of these patients for prevention of transfusion complications is important.
刚地弓形虫是一种专性细胞内原生动物寄生虫，是血液和组织中最重要的原生动物之一。这种寄生虫的医学重要性从先天性缺陷和先天性免疫缺陷患者中的感染机会两个方面来考虑。鉴于血液传播方式以及血液透析患者感染刚地弓形虫的风险，对伊朗人群进行了这项血清学研究。
本病例对照研究对37例接受定期血液透析的患者进行，其中男性21例，女性16例，平均年龄为17.52±4.10岁（年龄范围13 - 22岁）。选择37名健康个体作为对照组。所有样本采用ELISA试剂盒通过IgG - ELISA和IgM - ELISA两种方法进行检测。最后获得的数据用SPSS软件进行分析。
本研究结果显示血液透析患者中弓形虫病的患病率较高。其他研究结果表明，病例组37例患者中有21例抗刚地弓形虫IgG呈阳性，而对照组只有11例呈阳性，差异具有统计学意义（p <0.05）。
由于血液透析患者中弓形虫病的患病率较高，识别这些患者以预防输血并发症很重要。
