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了解你的邻居：不同的肿瘤微环境对髓母细胞瘤各亚组的免疫治疗靶向策略具有影响。

Know your neighbors: Different tumor microenvironments have implications in immunotherapeutic targeting strategies across MB subgroups.

作者信息

Pham Christina D, Mitchell Duane A

机构信息

Preston A. Wells, Jr. Center for Brain Tumor Therapy, Department of Neurosurgery, University of Florida , Gainesville, FL, USA.

出版信息

Oncoimmunology. 2016 Feb 18;5(11):e1144002. doi: 10.1080/2162402X.2016.1144002. eCollection 2016.

DOI:10.1080/2162402X.2016.1144002
PMID:27999733
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5139647/
Abstract

Medulloblastoma (MB) is the most common pediatric brain tumor with few reports of successful immunologic targeting. We have recently demonstrated the immune tumor microenvironment as well as response to immune checkpoint blockade differ across subtypes of murine MB.

摘要

髓母细胞瘤（MB）是最常见的儿童脑肿瘤，关于成功进行免疫靶向治疗的报道很少。我们最近证明，免疫肿瘤微环境以及对免疫检查点阻断的反应在小鼠MB的不同亚型之间存在差异。

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引用本文的文献

[1]
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[2]
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[3]
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[4]
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[5]
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[6]
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[7]
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Bioengineering (Basel). 2018-9-23

[8]
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本文引用的文献

[1]
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[2]
Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma.

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