Brandt B, Mortensen T, Bokmand S
Ugeskr Laeger. 1989 Sep 11;151(37):2371-3.
In a material of 25 patients with gastro-oesophageal reflux (GER), 11 had cerebral damage, 15 had symptoms of oesophagitis and 18 had respiratory problems including here six cases of apnoea with cyanosis and bradycardia resembling near-miss sudden infant death syndrome (SIDS). Only two of the children recovered acceptably on conservative treatment and the remainder were submitted to operation. Operation had insufficient effect in 30%. Cerebral damage or atresia of the oesophagus were present in all of the patients in whom operation was without effect. All children with symptom-producing GER should first be submitted to conservative treatment for at least three months and operation should be offered in cases where this treatment fails. Children with chronic or recurrent respiratory symptoms without other explanation and all children with episodes of apnoea and near-miss SIDS should be examined for the presence of GER.
在25例胃食管反流（GER）患儿中，11例有脑损伤，15例有食管炎症状，18例有呼吸问题，其中6例出现呼吸暂停伴发绀和心动过缓，类似婴儿猝死综合征（SIDS）的濒死状态。只有2例患儿经保守治疗后恢复良好，其余患儿接受了手术治疗。手术效果不佳的占30%。手术无效的所有患儿均存在脑损伤或食管闭锁。所有有症状的GER患儿均应首先接受至少三个月的保守治疗，若治疗失败则应考虑手术。对于有慢性或反复出现的无法解释的呼吸道症状的患儿以及所有有呼吸暂停发作和类似SIDS濒死状态的患儿，均应检查是否存在GER。
